(Q30434275)

21 June 2017

title

CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium (English)

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21 June 2017

Jiangli Yan

1

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21 June 2017

Yizhou Liu

2

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21 June 2017

Stephen M Lukasik

3

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21 June 2017

Nancy A Speck

4

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21 June 2017

John H Bushweller

5

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21 June 2017

publication date

22 August 2004

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Nature Structural & Molecular Biology

21 June 2017

published in

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21 June 2017

volume

11

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21 June 2017

issue

9

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21 June 2017

page(s)

901-906

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The Runt domain identifies a new family of heteromeric transcriptional regulators.

21 June 2017

cites work

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Biophysical characterization of interactions between the core binding factor alpha and beta subunits and DNA.

21 January 2018

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The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp

21 January 2018

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The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding

21 January 2018

1 reference

Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta

21 January 2018

1 reference

DNA recognition by the RUNX1 transcription factor is mediated by an allosteric transition in the RUNT domain and by DNA bending

21 January 2018

1 reference

Molecular dynamics and NMR spin relaxation in proteins

21 January 2018

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NMR methods for characterizing microsecond to millisecond dynamics in recognition and catalysis

21 January 2018

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Dynamic activation of protein function: a view emerging from NMR spectroscopy.

21 January 2018

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Nmr probes of molecular dynamics: overview and comparison with other techniques

21 January 2018

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Protein dynamics from NMR.

21 January 2018

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The Ig fold of the core binding factor alpha Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains

21 January 2018

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An optimized PCR-based procedure for production of 13C/15N-labeled DNA.

21 January 2018

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Distinctive DNA conformation with enlarged major groove is found in Zn-finger-DNA and other protein-DNA complexes

21 January 2018

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Energetic contribution of residues in the Runx1 Runt domain to DNA binding.

21 January 2018

1 reference

Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit

21 January 2018

1 reference

Multiple conformational changes in enzyme catalysis

21 January 2018

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Allosteric regulation of aspartate transcarbamoylase. Analysis of the structural and functional behavior in terms of a two-state model

21 January 2018

1 reference

Kinetics of allosteric enzymes

21 January 2018

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The contribution of individual interchain interactions to the stabilization of the T and R states of Escherichia coli aspartate transcarbamoylase

21 January 2018

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The role of intersubunit interactions for the stabilization of the T state of Escherichia coli aspartate transcarbamoylase

21 January 2018

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Biochemical and biophysical properties of the core-binding factor alpha2 (AML1) DNA-binding domain.

21 January 2018

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Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

21 January 2018

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An improved method for distinguishing between anisotropic tumbling and chemical exchange in analysis of 15N relaxation parameters

21 January 2018

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Backbone dynamics of proteins as studied by 15N inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease

21 January 2018

1 reference

Long-range motional restrictions in a multidomain zinc-finger protein from anisotropic tumbling.

21 January 2018

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Backbone dynamics of Escherichia coli ribonuclease HI: correlations with structure and function in an active enzyme

21 January 2018

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Isothermal titration calorimetry of protein-protein interactions

21 January 2018

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An effective method for the discrimination of motional anisotropy and chemical exchange

21 January 2018

1 reference

Two-state allosteric behavior in a single-domain signaling protein

31 March 2020

1 reference

Dynamics of methyl groups in proteins as studied by proton-detected 13C NMR spectroscopy. Application to the leucine residues of staphylococcal nuclease

31 March 2020

1 reference

Rotational diffusion anisotropy of proteins from simultaneous analysis of 15N and 13C alpha nuclear spin relaxation

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB819

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21 June 2017

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