(Q30435066)

19 October 2017

Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes (English)

1 reference

polycystic kidney disease

19 October 2017

1 reference

Almira Kurbegovic

1

1 reference

19 October 2017

Olivier Côté

2

1 reference

19 October 2017

Martin Couillard

3

1 reference

19 October 2017

Christopher J Ward

4

1 reference

19 October 2017

Peter C Harris

5

1 reference

19 October 2017

Marie Trudel

6

1 reference

19 October 2017

language of work or name

1 reference

6 January 2010

1 reference

19 October 2017

Human Molecular Genetics

1 reference

19 October 2017

19

1 reference

19 October 2017

7

1 reference

19 October 2017

1174-1189

1 reference

C-myc as a modulator of renal stem/progenitor cell population

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Characterization of PKD protein-positive exosome-like vesicles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Association of serum phosphate with vascular and valvular calcification in moderate CKD.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Large-scale proteomics and phosphoproteomics of urinary exosomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Pkd1 inactivation induced in adulthood produces focal cystic disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Characterization of cis-autoproteolysis of polycystin-1, the product of human polycystic kidney disease 1 gene.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

PKD1 haploinsufficiency causes a syndrome of inappropriate antidiuresis in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Overexpression of PKD1 causes polycystic kidney disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Identification and proteomic profiling of exosomes in human urine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Expression of PKD1 and PKD2 transcripts and proteins in human embryo and during normal kidney development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Polycystin 1 is required for the structural integrity of blood vessels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Coordinate expression of the autosomal dominant polycystic kidney disease proteins, polycystin-2 and polycystin-1, in normal and cystic tissue.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

C-myc-induced apoptosis in polycystic kidney disease is Bcl-2 and p53 independent

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Loss of the polycystic kidney disease (PKD1) region of chromosome 16p13 in renal cyst cells supports a loss-of-function model for cyst pathogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Identification and localization of polycystin, the PKD1 gene product

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Characterization and cell distribution of polycystin, the product of autosomal dominant polycystic kidney disease gene 1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Renal stone disease in autosomal dominant polycystic kidney disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Cardiovascular Abnormalities Associated with Adult Polycystic Kidney Disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Echocardiographic Findings in Autosomal Dominant Polycystic Kidney Disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

The Association of Nephrolithiasis and Autosomal Dominant Polycystic Kidney Disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

c-myc as an inducer of polycystic kidney disease in transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.

20 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

Murine Pkd1 is a developmentally regulated gene from morula to adulthood: role in tissue condensation and patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

Distinct and common developmental expression patterns of the murine Pkd2 and Pkd1 genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

A mouse model for polycystic kidney disease through a somatic in-frame deletion in the 5' end of Pkd1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

Polycystic kidneys caused by sustained expression of Cux1 isoform p75.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

Polycystin expression during embryonic development of human kidney in adult tissues and ADPKD tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP588

c-myc-induced apoptosis in polycystic kidney disease is independent of FasL/Fas interaction.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Vascular expression of polycystin.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease (ADPKD).

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081642

Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects

26 November 2018

1 reference

12 December 2020

Calcified renal stones and cyst calcifications in autosomal dominant polycystic kidney disease: clinical and CT study in 84 patients

1 reference

12 December 2020

A model of polycystic kidney disease in SBM transgenic mice

1 reference

12 December 2020

Intracranial aneurysms in autosomal dominant polycystic kidney disease

1 reference

12 December 2020

The transgenic SAD mouse: a model of human sickle cell glomerulopathy

1 reference

12 December 2020

Adult, fetal, and polycystic kidney expression of polycystin, the polycystic kidney disease-1 gene product

1 reference

12 December 2020

Immunolocalization of polycystin in human tissues and cultured cells

1 reference

12 December 2020

Loss of heterozygosity in polycystic kidney disease with a missense mutation in the repeated region of PKD1

1 reference

12 December 2020

Late onset of renal and hepatic cysts in Pkd1-targeted heterozygotes

1 reference

12 December 2020

Cellular localization and tissue distribution of polycystin-1

1 reference

12 December 2020

Polycystin-1 expression in PKD1, early-onset PKD1, and TSC2/PKD1 cystic tissue

1 reference

12 December 2020

Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease

1 reference

12 December 2020

Characterization of circulatory disorders in beta-thalassemic mice by noninvasive ultrasound biomicroscopy

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDP588

1 reference

19 October 2017

1 reference

19 October 2017

PubMed publication ID

20053665

1 reference