(Q30436718)

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Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

12

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Philippe Clézardin

object named as

Philippe Clézardin

14

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author name string

Marion David

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Estelle Wannecq

2

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Europe PubMed Central

PMC publication ID

13 September 2017

Françoise Descotes

3

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Silvia Jansen

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Blandine Deux

5

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Europe PubMed Central

PMC publication ID

13 September 2017

Johnny Ribeiro

6

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Claire-Marie Serre

7

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Nathalie Bendriss-Vermare

9

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Mathieu Bollen

10

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Simone Saez

11

1 reference

Europe PubMed Central

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13 September 2017

Olivier Peyruchaud

15

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Europe PubMed Central

PMC publication ID

13 September 2017

language of work or name

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publication date

17 March 2010

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Europe PubMed Central

PMC publication ID

13 September 2017

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

e9741

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

copyright license

Creative Commons Attribution 4.0 International

17 March 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Gene expression profiles of lysophosphatidic acid-related molecules in the prostate: relevance to prostate cancer and benign hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Sharpening the edges of understanding the structure/function of the LPA1 receptor: expression in cancer and mechanisms of regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Reduced expression of autotaxin predicts survival in uveal melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Synthesis and biological evaluation of phosphonate derivatives as autotaxin (ATX) inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Transcriptome analysis reveals an osteoblast-like phenotype for human osteotropic breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Lysophosphatidic acid induces chemotaxis in MC3T3-E1 osteoblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

NPP-type ectophosphodiesterases: unity in diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Breast cancer metastasis: markers and models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Molecular profile of catabolic versus anabolic treatment regimens of parathyroid hormone (PTH) in rat bone: an analysis by DNA microarray

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Expression, regulation and function of autotaxin in thyroid carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Angiostatin inhibits bone metastasis formation in nude mice through a direct anti-osteoclastic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

A multigenic program mediating breast cancer metastasis to bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Metastasis to bone: causes, consequences and therapeutic opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Lysophosphatidic acid is an osteoblast mitogen whose proliferative actions involve G(i) proteins and protein kinase C, but not P42/44 mitogen-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Hyperparathyroid and hypoparathyroid disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

American Society of Clinical Oncology guideline on the role of bisphosphonates in breast cancer. American Society of Clinical Oncology Bisphosphonates Expert Panel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Autotaxin expression in non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Expression and transcriptional regulation of the PD-Ialpha/autotaxin gene in neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Autotaxin is an exoenzyme possessing 5'-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

20 June 2018

In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

26 November 2018

Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

26 November 2018

Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

26 November 2018

Lysophosphatidic acid induces osteocyte dendrite outgrowth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

26 November 2018

Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

26 November 2018

Serum lysophosphatidic acid is produced through diverse phospholipase pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

26 November 2018

A novel orthotopic model of breast cancer metastasis to bone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

26 November 2018

The bioactive phospholipid lysophosphatidic acid is released from activated platelets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840030

26 November 2018

Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20305819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of autotaxin mRNA in human hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20305819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20305819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid cooperates with 1alpha,25(OH)2D3 in stimulating human MG63 osteoblast maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20305819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20305819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0009741

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

2010PLoSO...5.9741D

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

ResearchGate publication ID

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