(Q30438457)

21 June 2017

title

Farnesylthiosalicylic acid induces caspase activation and apoptosis in glioblastoma cells (English)

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21 June 2017

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Amos S

1

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21 June 2017

Redpath GT

2

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21 June 2017

Polar G

3

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21 June 2017

McPheson R

4

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21 June 2017

Schiff D

5

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21 June 2017

Hussaini IM

6

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21 June 2017

publication date

1 April 2006

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Cell Death & Differentiation

21 June 2017

published in

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21 June 2017

volume

13

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21 June 2017

issue

4

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21 June 2017

page(s)

642-651

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Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation

21 June 2017

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Roles of the functional loss of p53 and other genes in astrocytoma tumorigenesis and progression

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B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

21 January 2018

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The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal

21 January 2018

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Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas.

21 January 2018

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7 January 2021

Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas.

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7 January 2021

Malignant glioma: genetics and biology of a grave matter.

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7 January 2021

PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy

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7 January 2021

Enhanced radiosensitivity of malignant glioma cells after adenoviral p53 transduction

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7 January 2021

Targeted molecular therapy of GBM.

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7 January 2021

Intercellular junctions: downstream and upstream of Ras?

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Developmentally-regulated expression of murine K-ras isoforms.

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7 January 2021

Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Protein prenylation, et cetera: signal transduction in two dimensions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Characterization of Ha-ras, N-ras, Ki-Ras4A, and Ki-Ras4B as in vitro substrates for farnesyl protein transferase and geranylgeranyl protein transferase type I

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Cellular survival: a play in three Akts

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Dislodgment and accelerated degradation of Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Novel Ras antagonist blocks human melanoma growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Protein isoprenylation and methylation at carboxyl-terminal cysteine residues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Farnesyl thiosalicylic acid inhibits the growth of melanoma cells through a combination of cytostatic and pro-apoptotic effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

The novel Ras antagonist, farnesylthiosalicylate, suppresses growth of prostate cancer in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

The Ras inhibitor S-trans, trans-farnesylthiosalicylic acid exerts long-lasting neuroprotection in a mouse closed head injury model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Phorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401783

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401783

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21 June 2017

1 reference