(Q30439607)

English

Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65. (English)

1 reference

Europe PubMed Central

15 August 2017

0 references

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Kaiser M Bijli

1

1 reference

Europe PubMed Central

15 August 2017

Fabeha Fazal

2

1 reference

Europe PubMed Central

15 August 2017

Mohd Minhajuddin

3

1 reference

Europe PubMed Central

15 August 2017

Arshad Rahman

4

1 reference

Europe PubMed Central

15 August 2017

language of work or name

0 references

publication date

24 March 2008

1 reference

Europe PubMed Central

15 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

15 August 2017

283

1 reference

Europe PubMed Central

15 August 2017

21

1 reference

Europe PubMed Central

15 August 2017

14674-14684

1 reference

Europe PubMed Central

15 August 2017

Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

c-Src mediates thrombin-induced NF-kappaB activation and IL-8/CXCL8 expression in lung epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Src and Syk kinases: key regulators of phagocytic cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

The non-receptor tyrosine kinase Syk regulates lamellipodium formation and site-directed migration of human leukocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Functional role of c-Src in IL-1-induced NF-kappa B activation: c-Src is a component of the IKK complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Syk tyrosine kinase participates in beta1-integrin signaling and inflammatory responses in airway epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Nuclear factor-kappaB: the enemy within

1 reference

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20 June 2018

Signaling to NF-kappaB

1 reference

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20 June 2018

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

1 reference

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20 June 2018

Role of protein kinase C isoforms in the regulation of interleukin-13-induced 15-lipoxygenase gene expression in human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Activation of Syk protein tyrosine kinase in response to osmotic stress requires interaction with p21-activated protein kinase Pak2/gamma-PAK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Thrombin and Phenotypic Modulation of the Endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Tyrosine Kinase p56 Regulates Cell Motility and Nuclear Factor κB-mediated Secretion of Urokinase Type Plasminogen Activator through Tyrosine Phosphorylation of IκBα following Hypoxia/Reoxygenation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Induction of cIAP-2 in Human Colon Cancer Cells through PKCδ/NF-κB

1 reference

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20 June 2018

Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Regulation of airway epithelial cell NF-kappa B-dependent gene expression by protein kinase C delta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Ras regulation of NF-kappa B and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Tyrosine kinase SYK: essential functions for immunoreceptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element

1 reference

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20 June 2018

The Syk family of protein tyrosine kinases in T-cell activation and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Antisense oligonucleotides targeting protein kinase C-alpha, -beta I, or -delta but not -eta inhibit lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages: involvement of a nuclear factor kappa B-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Syk activation is required for spreading and H2O2 release in adherent human neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

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20 June 2018

Reduction of mortality with antithrombin III in septicemic rats: a study of Klebsiella pneumoniae induced sepsis.

1 reference

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20 June 2018

The sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-src

1 reference

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Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

1 reference

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Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

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20 June 2018

Thrombin specificity

1 reference

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Immunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells

1 reference

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Human vascular endothelial cells in culture. Growth and DNA synthesis

1 reference

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1 reference

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Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

20 June 2018

Role of p34cdc2-mediated phosphorylations in two-step activation of pp60c-src during mitosis

1 reference

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Structural analysis of the avian sarcoma virus transforming protein: sites of phosphorylation

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20 June 2018

Neutrophil adhesion to endothelial cells induced by platelet factor 4 requires sequential activation of Ras, Syk, and JNK MAP kinases

1 reference

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26 November 2018

Protein kinase Cdelta mediates lysophosphatidic acid-induced NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells

1 reference

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26 November 2018

cAMP targeting of p38 MAP kinase inhibits thrombin-induced NF-kappaB activation and ICAM-1 expression in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386948

26 November 2018

TNF activates Syk protein tyrosine kinase leading to TNF-induced MAPK activation, NF-kappaB activation, and apoptosis

1 reference

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26 November 2018

Integrins and cytokines activate nuclear transcription factor-kappaB in human neutrophils

1 reference

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26 November 2018

Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase

1 reference

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26 November 2018

Tyrosine Phosphorylation of I-κB Kinase α/β by Protein Kinase C-Dependent c-Src Activation Is Involved in TNF-α-Induced Cyclooxygenase-2 Expression

1 reference

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26 November 2018

Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation.

1 reference

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26 November 2018

Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase

1 reference

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26 November 2018

Syk is required for integrin signaling in neutrophils

1 reference

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26 November 2018

Syk expression in endothelial cells and their morphologic defects in embryonic Syk-deficient mice

1 reference

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26 November 2018

NF-kappa B activation in tumor necrosis factor alpha-stimulated neutrophils is mediated by protein kinase Cdelta. Correlation to nuclear Ikappa Balpha

1 reference

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26 November 2018

Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aerosolized Syk antisense suppresses Syk expression, mediator release from macrophages, and pulmonary inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD11/CD18-dependent and -independent neutrophil emigration in the lungs: how do neutrophils know which route to take?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical role for Syk in endothelial cell proliferation and migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin, TNF-alpha, and LPS exert overlapping but nonidentical effects on gene expression in endothelial cells and vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M802094200

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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