(Q30445485)

English

Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells (English)

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

0 references

author name string

William A Sands

1

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Hayley D Woolson

2

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Gillian R Milne

3

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Claire Rutherford

4

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Timothy M Palmer

5

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

language of work or name

0 references

publication date

1 September 2006

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

26

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

17

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

6333-6346

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons

1 reference

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Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases

1 reference

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Spatial and temporal dynamics of the endothelium

1 reference

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Endothelial inflammation in insulin resistance

1 reference

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Activation of SOCS-3 by resistin

1 reference

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Interleukin-6 induced basic fibroblast growth factor-dependent angiogenesis in basal cell carcinoma cell line via JAK/STAT3 and PI3-kinase/Akt pathways.

1 reference

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20 June 2018

Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway

1 reference

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MAP1A light chain 2 interacts with exchange protein activated by cyclic AMP 1 (EPAC1) to enhance Rap1 GTPase activity and cell adhesion.

1 reference

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Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis.

1 reference

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Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: advances in the development of specific phosphodiesterase inhibitors

1 reference

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20 June 2018

Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

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Epac- and Ca2+ -controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors

1 reference

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The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin

1 reference

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The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

1 reference

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20 June 2018

Localized effects of cAMP mediated by distinct routes of protein kinase A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

20 June 2018

Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

20 June 2018

Suppressors of cytokine signaling and immunity

1 reference

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20 June 2018

Inhibitors of cytokine signal transduction

1 reference

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The ins and outs of leptin receptor activation

1 reference

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Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling.

1 reference

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

1 reference

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SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation

1 reference

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20 June 2018

SOCS3 negatively regulates IL-6 signaling in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

20 June 2018

Interleukins in atherosclerosis: molecular pathways and therapeutic potential

1 reference

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20 June 2018

Cloning and characterization of a functional promoter of the human SOCS-3 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

20 June 2018

Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

20 June 2018

The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

20 June 2018

Prostaglandin E2 promotes integrin alpha Vbeta 3-dependent endothelial cell adhesion, rac-activation, and spreading through cAMP/PKA-dependent signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

20 June 2018

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

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Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.

1 reference

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Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B

1 reference

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Pim serine/threonine kinases regulate the stability of Socs-1 protein

1 reference

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Oncostatin M regulates the synthesis and turnover of gp130, leukemia inhibitory factor receptor alpha, and oncostatin M receptor beta by distinct mechanisms.

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The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.

1 reference

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SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

1 reference

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Thyrotropin induces SOCS-1 (suppressor of cytokine signaling-1) and SOCS-3 in FRTL-5 thyroid cells

1 reference

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Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma.

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Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

1 reference

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

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Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

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Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.

1 reference

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Action of cAMP on expression and release of adhesion molecules in human endothelial cells

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Epac: a new cAMP target and new avenues in cAMP research

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592846

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IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

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based on heuristic

inferred from PubMed ID database lookup

Stimulation of the mitogen-activated protein kinase via the A2A-adenosine receptor in primary human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16914720

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epac1 regulates integrity of endothelial cell junctions through VE-cadherin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16914720

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00207-06

1 reference

https://api.fatcat.wiki/v0/release/p5p225prmva2paokwtfc5ftumy

30 July 2022

based on heuristic

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release_p5p225prmva2paokwtfc5ftumy

1 reference

https://api.fatcat.wiki/v0/release/p5p225prmva2paokwtfc5ftumy

30 July 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

https://api.fatcat.wiki/v0/release/p5p225prmva2paokwtfc5ftumy

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/p5p225prmva2paokwtfc5ftumy

30 July 2022

based on heuristic

mapped directly with Wikidata item

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