(Q30448335)

English

In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease (English)

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Amy K Patick

1

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Mary A Brothers

2

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Fausto Maldonado

3

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Susan Binford

4

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Oscar Maldonado

5

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Shella Fuhrman

6

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Annkatrin Petersen

7

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

George J Smith

8

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Leora S Zalman

9

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Leigh Ann Burns-Naas

10

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Jonathan Q Tran

11

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

language of work or name

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publication date

1 June 2005

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

49

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

6

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

2267-2275

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers

1 reference

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28 July 2018

Combined antiviral-antimediator treatment for the common cold

1 reference

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28 July 2018

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. Part 7: structure-activity studies of bicyclic 2-pyridone-containing peptidomimetics

1 reference

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28 July 2018

Treatment of potentially life-threatening enterovirus infections with pleconaril

1 reference

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28 July 2018

In vitro activity of pleconaril and AG7088 against selected serotypes and clinical isolates of human rhinoviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Inhibition of human rhinovirus-induced cytokine production by AG7088, a human rhinovirus 3C protease inhibitor

1 reference

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28 July 2018

In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Respiratory tract viral infections in inner-city asthmatic adults

1 reference

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28 July 2018

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Synthesis and evaluation of peptidyl Michael acceptors that inactivate human rhinovirus 3C protease and inhibit virus replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Effects of upper respiratory tract infections in patients with cystic fibrosis

1 reference

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28 July 2018

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

The association of rhinoviruses with lower respiratory tract disease in hospitalized patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Site-directed mutagenesis suggests close functional relationship between a human rhinovirus 3C cysteine protease and cellular trypsin-like serine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

The major and minor group receptor families contain all but one human rhinovirus serotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Treatment of the picornavirus common cold by inhibitors of viral uncoating and attachment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

28 July 2018

Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140523

26 November 2018

Substitution Mutations at the Putative Catalytic Triad of the Poliovirus 3C Protease Have Differential Effects on Cleavage at Different Sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/15917520

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of rhinovirus in induced sputum at exacerbation of chronic obstructive pulmonary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15917520

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.49.6.2267-2275.2005

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

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