(Q30452219)

21 June 2017

title

Improving the radiosensitivity of radioresistant and hypoxic glioblastoma (English)

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21 June 2017

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1

Jason P Sheehan

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21 June 2017

Mark E Shaffrey

2

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21 June 2017

Brinda Gupta

3

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21 June 2017

James Larner

4

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21 June 2017

Jeremy N Rich

5

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21 June 2017

Deric M Park

6

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21 June 2017

language of work or name

English

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publication date

1 October 2010

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21 June 2017

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21 June 2017

volume

6

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21 June 2017

issue

10

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21 June 2017

page(s)

1591-1601

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Medical oncology: treatment and management of malignant gliomas

21 June 2017

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HIF-1: using two hands to flip the angiogenic switch

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Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity

21 January 2018

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The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy.

21 January 2018

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21 January 2018

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Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan

21 January 2018

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21 January 2018

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Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

21 January 2018

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Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.

21 January 2018

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Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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N-CoR pathway targeting induces glioblastoma derived cancer stem cell differentiation

21 January 2018

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21 January 2018

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21 January 2018

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Chemical genetics reveals a complex functional ground state of neural stem cells

21 January 2018

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Brain cancer stem cells display preferential sensitivity to Akt inhibition

21 January 2018

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

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Inhibition of phosphatidylinositol-3-OH kinase/Akt signaling impairs DNA repair in glioblastoma cells following ionizing radiation

21 January 2018

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

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Hypoxia and defective apoptosis drive genomic instability and tumorigenesis

21 January 2018

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Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells

21 January 2018

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Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

21 January 2018

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Hypoxic radiosensitization: adored and ignored

21 January 2018

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The impact of hemoglobin levels on treatment outcomes in patients with cancer

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The importance of the pre-irradiation breathing times of oxygen and carbogen (5% CO2: 95% O2) on the in vivo radiation response of a murine sarcoma

21 January 2018

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21 January 2018

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21 January 2018

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Effect of trans sodium crocetinate on brain tumor oxygenation. Laboratory investigation

21 January 2018

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trans-Sodium crocetinate and diffusion enhancement

21 January 2018

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Use of trans sodium crocetinate for sensitizing glioblastoma multiforme to radiation: laboratory investigation

21 January 2018

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Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

21 January 2018

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AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

21 January 2018

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Improved intratumoral oxygenation through vascular normalization increases glioma sensitivity to ionizing radiation

21 January 2018

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Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma

21 January 2018

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Continuous delivery of IFN-beta promotes sustained maturation of intratumoral vasculature.

21 January 2018

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TGF-beta, neuronal stem cells and glioblastoma

21 January 2018

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Influence of bromodeoxyuridine radiosensitization on malignant glioma patient survival: a retrospective comparison of survival data from the Northern California Oncology Group (NCOG) and Radiation Therapy Oncology Group trials (RTOG) for glioblastom

21 January 2018

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Tamoxifen radiosensitization in human glioblastoma cell lines

21 January 2018

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Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture.

21 January 2018

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Daily low-dose carboplatin as a radiation sensitizer for newly diagnosed malignant glioma.

21 January 2018

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Time and dose-dependent radiosensitization of the glioblastoma multiforme U251 cells by the EGF receptor tyrosine kinase inhibitor ZD1839 ('Iressa').

21 January 2018

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MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells

21 January 2018

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Novel radiation-enhancing agents in malignant gliomas

21 January 2018

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High-grade astrocytoma treated concomitantly with estramustine and radiotherapy

21 January 2018

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Motexafin gadolinium combined with prompt whole brain radiotherapy prolongs time to neurologic progression in non-small-cell lung cancer patients with brain metastases: results of a phase III trial

21 January 2018

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Results of the phase I dose-escalating study of motexafin gadolinium with standard radiotherapy in patients with glioblastoma multiforme

21 January 2018

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Motexafin gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: a Children's Oncology Group phase I study

21 January 2018

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https://api.crossref.org/works/10.2217%2FFON.10.123

RSR13 plus cranial radiation therapy in patients with brain metastases: comparison with the Radiation Therapy Oncology Group Recursive Partitioning Analysis Brain Metastases Database

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Therapeutic implications of cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

21 January 2018

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https://api.crossref.org/works/10.2217%2FFON.10.123

Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence

21 January 2018

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https://api.crossref.org/works/10.2217%2FFON.10.123

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Making a tumour's bed: glioblastoma stem cells and the vascular niche.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Integrin alpha 6 regulates glioblastoma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Cancer stem cells: mirage or reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Enhanced response to radiotherapy in tumours deficient in the function of hypoxia-inducible factor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules

21 January 2018

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https://api.crossref.org/works/10.2217%2FFON.10.123

Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

Bevacizumab plus irinotecan in recurrent glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.123

21 January 2018

Identifiers

DOI

10.2217/FON.10.123

1 reference

21 June 2017

1 reference