(Q30462749)

10 August 2017

Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior (English)

1 reference

Jeremy Veenstra-VanderWeele

10 August 2017

0 references

0 references

Jeremy Veenstra-VanderWeele

0 references

Brent J Thompson

Brent J Thompson

10

0 references

Ana M. D. Carneiro

Ana M Carneiro

13

0 references

Ana M. Carneiro

Ana M Carneiro

13

0 references

James S. Sutcliffe

James S Sutcliffe

19

0 references

author name string

Christopher L Muller

2

1 reference

10 August 2017

Hideki Iwamoto

3

1 reference

10 August 2017

Jennifer E Sauer

4

1 reference

10 August 2017

W Anthony Owens

5

1 reference

10 August 2017

Charisma R Shah

6

1 reference

10 August 2017

Jordan Cohen

7

1 reference

10 August 2017

Padmanabhan Mannangatti

8

1 reference

10 August 2017

Tammy Jessen

9

1 reference

10 August 2017

Ran Ye

11

1 reference

10 August 2017

Travis M Kerr

12

1 reference

10 August 2017

Jacqueline N Crawley

14

1 reference

10 August 2017

Elaine Sanders-Bush

15

1 reference

10 August 2017

Douglas G McMahon

16

1 reference

10 August 2017

Sammanda Ramamoorthy

17

1 reference

10 August 2017

Lynette C Daws

18

1 reference

10 August 2017

Randy D Blakely

20

1 reference

10 August 2017

language of work or name

English

0 references

publication date

19 March 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

1 reference

10 August 2017

109

1 reference

10 August 2017

14

1 reference

10 August 2017

5469-5474

1 reference

Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

A transient placental source of serotonin for the fetal forebrain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Serotonin mediates cross-modal reorganization of cortical circuits.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Behavioural phenotyping assays for mouse models of autism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Relationship between whole blood serotonin and repetitive behaviors in autism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Modeling rare gene variation to gain insight into the oldest biomarker in autism: construction of the serotonin transporter Gly56Ala knock-in mouse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Postnatal lesion evidence against a primary role for the corpus callosum in mouse sociability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

A large-scale screen for coding variants in SERT/SLC6A4 in autism spectrum disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Social approach in genetically engineered mouse lines relevant to autism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Enhanced activity of human serotonin transporter variants associated with autism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Calcium/calmodulin-dependent kinase II regulates the interaction between the serotonin transporter and syntaxin 1A.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Going with the flow: trafficking-dependent and -independent regulation of serotonin transport

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

A pharmacological analysis of mice with a targeted disruption of the serotonin transporter.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

3,4-Methylenedioxymethamphetamine- and 8-hydroxy-2-di-n-propylamino-tetralin-induced hypothermia: role and location of 5-hydroxytryptamine 1A receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Serotonin modulates the response of embryonic thalamocortical axons to netrin-1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Pten regulates neuronal arborization and social interaction in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

The N-terminus of the norepinephrine transporter regulates the magnitude and selectivity of the transporter-associated leak current

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

A genetic approach to access serotonin neurons for in vivo and in vitro studies.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Autism and the serotonin transporter: the long and short of it

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Sex-specific genetic architecture of whole blood serotonin levels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

A genomewide screen for autism: strong evidence for linkage to chromosomes 2q, 7q, and 16p.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Broad and narrow heritabilities of quantitative traits in a founder population

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Direct injection of 5-HT2A receptor agonists into the medial prefrontal cortex produces a head-twitch response in rats.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Functional expression of the plasma membrane serotonin transporter but not the vesicular monoamine transporter in human placental trophoblasts and choriocarcinoma cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Receptor stimulation causes slow inhibition of IRK1 inwardly rectifying K+ channels by direct protein kinase A-mediated phosphorylation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Determination of serotonin in whole blood, platelet-rich plasma, platelet-poor plasma and plasma ultrafiltrate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Platelet serotonin levels in pervasive developmental disorders and mental retardation: diagnostic group differences, within-group distribution, and behavioral correlates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Principal pathogenetic components and biological endophenotypes in autism spectrum disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Screening a large reference sample to identify very low frequency sequence variants: comparisons between two genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

In vivo chronoamperometric measurements of the clearance of exogenously applied serotonin in the rat dentate gyrus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Social and communication development in toddlers with early and later diagnosis of autism spectrum disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Sensorimotor gating deficits in adults with autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

A quantitative trait locus analysis of social responsiveness in multiplex autism families

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

A principal components analysis of the Autism Diagnostic Interview-Revised.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1112345109

Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325657

26 November 2018

Identifiers

DOI

10.1073/PNAS.1112345109

1 reference

10 August 2017

0 references

1 reference

10 August 2017

1 reference