(Q30465168)

19 October 2017

Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis (English)

1 reference

19 October 2017

3

Gwen Lomberk

1 reference

19 October 2017

Dominique Thabut

1

1 reference

19 October 2017

Chittaranjan Routray

2

1 reference

19 October 2017

Uday Shergill

4

1 reference

19 October 2017

Kevin Glaser

5

1 reference

19 October 2017

Robert Huebert

6

1 reference

19 October 2017

Leena Patel

7

1 reference

19 October 2017

Tetyana Masyuk

8

1 reference

19 October 2017

Boris Blechacz

9

1 reference

19 October 2017

Andrew Vercnocke

10

1 reference

19 October 2017

Erik Ritman

11

1 reference

19 October 2017

Richard Ehman

12

1 reference

19 October 2017

Raul Urrutia

13

1 reference

19 October 2017

Vijay Shah

14

1 reference

19 October 2017

language of work or name

English

0 references

publication date

26 June 2011

1 reference

19 October 2017

1 reference

19 October 2017

54

1 reference

19 October 2017

2

1 reference

19 October 2017

573-585

1 reference

Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: new targets for the treatment of portal hypertension?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Immortalized liver endothelial cells: a cell culture model for studies of motility and angiogenesis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Sorafenib: a clinical and pharmacologic review

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Pharmacological inhibition of integrin alphavbeta3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Sorafenib targets dysregulated Rho kinase expression and portal hypertension in rats with secondary biliary cirrhosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Tie2 is tied at the cell-cell contacts and to extracellular matrix by angiopoietin-1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Sorafenib in advanced hepatocellular carcinoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Magnetic resonance imaging of hepatic fibrosis: emerging clinical applications

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Disruption of an SP2/KLF6 repression complex by SHP is required for farnesoid X receptor-induced endothelial cell migration.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Discovery and development of sorafenib: a multikinase inhibitor for treating cancer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Signaling and functions of angiopoietin-1 in vascular protection.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Endothelial/pericyte interactions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Molecular regulation of vessel maturation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Three-dimensional imaging of vasculature and parenchyma in intact rodent organs with X-ray micro-CT.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Magnetic resonance elastography by direct visualization of propagating acoustic strain waves

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Hepatic stellate cells secrete angiopoietin 1 that induces angiogenesis in liver fibrosis.

20 June 2018

1 reference

Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.

21 January 2018

1 reference

Magnetic resonance elastography: non-invasive mapping of tissue elasticity.

21 January 2018

1 reference

Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation.

21 January 2018

1 reference

Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread.

21 January 2018

1 reference

Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats

21 January 2018

1 reference

Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.

21 January 2018

1 reference

Strengthening tight junctions of retinal microvascular endothelial cells by pericytes under normoxia and hypoxia involving angiopoietin-1 signal way.

21 January 2018

1 reference

Sp1 binding activity increases in activated Ito cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21567441

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21567441

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/HEP.24427

1 reference

19 October 2017

1 reference

19 October 2017

PubMed publication ID

21567441

1 reference