(Q30469104)

English

Murine alpha-macroglobulins demonstrate divergent activities as neutralizers of transforming growth factor-beta and as inducers of nitric oxide synthesis. A possible mechanism for the endotoxin insensitivity of the alpha2-macroglobulin gene knock-ou

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Europe PubMed Central

21 June 2017

Murine alpha-macroglobulins demonstrate divergent activities as neutralizers of transforming growth factor-beta and as inducers of nitric oxide synthesis. A possible mechanism for the endotoxin insensitivity of the alpha2-macroglobulin gene knock-ou (English)

1 reference

Europe PubMed Central

21 June 2017

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author name string

Webb DJ

1

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Europe PubMed Central

21 June 2017

Wen J

2

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Europe PubMed Central

21 June 2017

Lysiak JJ

3

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Europe PubMed Central

21 June 2017

Umans L

4

1 reference

Europe PubMed Central

21 June 2017

Van Leuven F

5

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Europe PubMed Central

21 June 2017

Gonias SL

6

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Europe PubMed Central

21 June 2017

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publication date

1 October 1996

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21 June 2017

Journal of Biological Chemistry

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Europe PubMed Central

21 June 2017

271

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21 June 2017

24982-24988

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Europe PubMed Central

21 June 2017

40

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Europe PubMed Central

21 June 2017

Pathogenetic mechanisms of septic shock

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Use of nitric oxide synthase inhibitors as a novel treatment for septic shock

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NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide

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Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock

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Nitric oxide synthases: roles, tolls, and controls

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Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter

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Altered immune responses in mice lacking inducible nitric oxide synthase

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Alpha 2-macroglobulin functions as a cytokine carrier to induce nitric oxide synthesis and cause nitric oxide-dependent cytotoxicity in the RAW 264.7 macrophage cell line

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21 January 2018

The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

1 reference

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21 January 2018

Physical properties of human alpha 2-macroglobulin following reaction with methylamine and trypsin.

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Identification of four genes coding for isoforms of murinoglobulin, the monomeric mouse alpha 2-macroglobulin: characterization of the exons coding for the bait region

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Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta

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21 January 2018

Kinetics of the reaction of streptokinase-plasmin complex with purified human and mouse alpha 2-macroglobulin. Implications for mechanism

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21 January 2018

Ligand binding, conformational change and plasma elimination of human, mouse and rat α-macroglobulin proteinase inhibitors

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Plasmin cleaves betaglycan and releases a 60 kDa transforming growth factor-beta complex from the cell surface

1 reference

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21 January 2018

Neurotrophin binding to human alpha 2-macroglobulin under apparent equilibrium conditions

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The role of cysteine-949 in the binding of transforming growth factor-beta 1 and transforming growth factor-beta 2 to alpha 2-macroglobulin

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Characterization of distinct functional domains of transforming growth factor beta

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

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Alpha 2-macroglobulin and the alpha 2-macroglobulin receptor/LRP. A growth regulatory axis

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Cloning and characterization of inducible nitric oxide synthase from mouse macrophages

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21 January 2018

Autocrine transforming growth factor beta 1 modulates the expression of integrin alpha 5 beta 1 in human colon carcinoma FET cells

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Native and activated forms of alpha 2-macroglobulin increase expression of platelet-derived growth factor alpha-receptor in vascular smooth muscle cells. Evidence for autocrine transforming growth factor-beta activity

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21 January 2018

TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector

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21 January 2018

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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21 January 2018

Transforming growth factor-beta 1 inhibits activation of macrophage cell line RAW 264.7 for cell killing

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21 January 2018

Expression and secretion of type beta transforming growth factor by activated human macrophages

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21 January 2018

Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta

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21 January 2018

Differences in the binding of transforming growth factor beta 1 to the acute-phase reactant and constitutively synthesized alpha-macroglobulins of rat.

1 reference

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21 January 2018

Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice

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Binding of platelet-derived growth factor-BB and transforming growth factor-beta 1 to alpha 2-macroglobulin in vitro and in vivo: comparison of receptor-recognized and non-recognized alpha 2-macroglobulin conformations

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21 January 2018

Identifiers

10.1074/JBC.271.40.24982

1 reference

Europe PubMed Central

21 June 2017

1 reference

Europe PubMed Central

21 June 2017

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