(Q30476415)

3 November 2017

1 reference

title

Osteosarcomagenesis: modeling cancer initiation in the mouse (English)

1 reference

3 November 2017

Kevin B Jones

1

1 reference

PMC publication ID

3043296

3 November 2017

language of work or name

1 reference

20 February 2011

1 reference

3 November 2017

1 reference

3 November 2017

2011

1 reference

3 November 2017

694136

1 reference

Creative Commons Attribution 3.0 Unported

3 November 2017

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Intermittent PTH1-34 causes DNA and chromosome breaks in osteoblastic and nonosteoblastic cells

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Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression

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Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy

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Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity

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Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality

20 June 2018

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Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice

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Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice

20 June 2018

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MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression

20 June 2018

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Murine osteosarcoma primary tumour growth and metastatic progression is maintained after marked suppression of serum insulin-like growth factor I.

20 June 2018

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20 June 2018

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Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

20 June 2018

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Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

20 June 2018

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Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha

20 June 2018

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Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis

20 June 2018

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20 June 2018

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Targeted deletion of Wwox reveals a tumor suppressor function

20 June 2018

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Compensation by tumor suppressor genes during retinal development in mice and humans

20 June 2018

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Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

20 June 2018

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Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice

20 June 2018

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Retroviral insertional mutagenesis: past, present and future

20 June 2018

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Diethylstilbestrol (DES): carcinogenic potential in Xpa-/-, Xpa-/- / p53+/-, and wild-type mice during 9 months' dietary exposure

20 June 2018

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Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

20 June 2018

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Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome

20 June 2018

1 reference

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Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

20 June 2018

1 reference

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Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130

20 June 2018

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Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

20 June 2018

1 reference

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Biology and therapeutic advances for pediatric osteosarcoma

20 June 2018

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The Runx genes: lineage-specific oncogenes and tumor suppressors

20 June 2018

1 reference

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The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Reduced growth of human sarcoma xenografts in hosts homozygous for the lit mutation

20 June 2018

1 reference

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Genomic instability, DNA methylation, and natural selection in colorectal carcinogenesis

20 June 2018

1 reference

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CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Transgenic mouse model for neurocristopathy: Schwannomas and facial bone tumors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Osteosarcomagenic doses of radium (224Ra) and infectious endogenous retroviruses enhance proliferation and osteogenic differentiation of skeletal tissue differentiating in vitro.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Tumor spectrum analysis in p53-mutant mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

The role of time-factor and RBE for the induction of osteosarcomas by incorporated short-lived bone-seekers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

FBR murine osteosarcoma virus. I. Molecular analysis and characterization of a 75,000-Da gag-fos fusion product

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Gamma-ray induction of malignant tumors in rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Radiation-induced sarcoma of bone

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Radiation Dose-time Relations for Induction of Osteosarcoma in Mice and Dogs and Their Bearing on Maximal Permissible Burden of 90Sr in Man

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

The induction by 239Pu of myeloid leukaemia and osteosarcoma in female CBA mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

A cancer family syndrome in twenty-four kindreds

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Osteosarcomas in transgenic mice expressing an alpha-amylase-SV40 T-antigen hybrid gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Requirement for a functional Rb-1 gene in murine development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Inhibition of Metastatic Behavior of Murine Osteosarcoma by Hypophysectomy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Experimental induction of bone tumors by short-lived bone-seeking radionuclides

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

DMBA-induced fibrosarcoma in bone. Histochemical and electron microscopical studies on new transplantable bone tumor of 7,12-dimethylbenz(alpha)anthracene-induced fibrosarcoma in rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Aspects of the dosimetry of alpha-emitting radionuclides in bone with particular emphasis of 226Ra and 239Pu

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Pathogenesis of Radiation and Virus-Induced Bone Tumors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Difference in the induction of osteosarcoma in rabbit bone with single administration of three kinds of chemical carcinogens

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Induction of murine fibrosarcomas by low dose treatment with 3-methylcholanthrene followed by promotion with 12-O-tetradecanoyl-phorbol-13-acetate.

20 June 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

Cancer in offspring of parents engaged in agricultural activities in Norway: incidence and risk factors in the farm environment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

Occupational factors and risk of adult bone sarcomas: a multicentric case-control study in Europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

THE PRODUCTION OF OSTEOGENIC SARCOMATA AND THE EFFECTS ON LYMPH NODES AND BONE MARROW OF INTRAVENOUS INJECTIONS OF RADIUM CHLORIDE AND MESOTHORIUM IN RABBITS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

Bone cancer risk in mice exposed to 224Ra: protraction effects from promotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

Spontaneous and irradiation-induced tumor susceptibility in BRCA2 germline mutant mice and cooperative effects with a p53 germline mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

Growth retardation and skin abnormalities of the Recql4-deficient mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

The specific induction of osteosarcomas in different mouse strains after injections of 239Pu citrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

Defining a noncarcinogenic dose of recombinant human parathyroid hormone 1-84 in a 2-year study in Fischer 344 rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2011%2F694136

Prognostic implication of immunohistochemical Runx2 expression in osteosarcoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

c-fos-induced osteosarcoma formation in transgenic mice: cooperativity with c-jun and the role of endogenous c-fos

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Smooth muscle and bone neoplasms in transgenic mice expressing SV40 T antigen.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

c-fos expression induces bone tumors in transgenic mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043296

Expression of protooncogenes in murine osteosarcomas

26 November 2018

1 reference

12 December 2020

The NF2 gene and merlin protein in human osteosarcomas

1 reference

12 December 2020

Bilateral Nonpalpable Breast Carcinomas in a Patient with BRCA2 Germ Line Mutation and Past History of Osteosarcoma

1 reference

12 December 2020

Osteosarcoma: pathology and classification

1 reference

12 December 2020

Genetic background alters the spectrum of tumors that develop in p53-deficient mice

1 reference

12 December 2020

Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1-34) for 2 years and relevance to human safety

1 reference

12 December 2020

Expression and immune recognition of SV40 Tag in transgenic mice that develop metastatic osteosarcomas

1 reference

12 December 2020

Experimental studies on high-dose methotrexate with citrovorum factor chemotherapy for 89Sr-induced osteosarcoma murine model

1 reference

12 December 2020

Induction of Neoplasia by140Ba in Mice

1 reference

12 December 2020

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

12 December 2020

Lack of suppressor cell activity in the spleens of mice with radiation-induced osteogenic sarcomas

1 reference

12 December 2020

Viruses in osteosarcomas induced by 226Ra. A study of the induction of bone tumours in mice

1 reference

12 December 2020

The sensitivity of female NMRI mice of different ages for osteosarcoma induction with 227thorium

1 reference

12 December 2020

Low-grade intraosseous osteosarcoma

1 reference

12 December 2020

Identifiers

DOI

10.1155/2011/694136

1 reference

3 November 2017

1 reference

PMC publication ID

3043296

3 November 2017

PubMed publication ID

21403899

1 reference

PMC publication ID

3043296