(Q30476509)

English

Perspective on post-menopausal osteoporosis: establishing an interdisciplinary understanding of the sequence of events from the molecular level to whole bone fractures

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scholarly article

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Europe PubMed Central

PMC publication ID

14 September 2017

1 reference

Europe PubMed Central

Perspective on post-menopausal osteoporosis: establishing an interdisciplinary understanding of the sequence of events from the molecular level to whole bone fractures (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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inferred from title

Laoise McNamara

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object named as

L M McNamara

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Europe PubMed Central

PMC publication ID

14 September 2017

publication date

21 October 2009

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Europe PubMed Central

PMC publication ID

14 September 2017

Journal of the Royal Society Interface

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Europe PubMed Central

PMC publication ID

14 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

44

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

353-372

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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Loss of trabeculae by mechano-biological means may explain rapid bone loss in osteoporosis

1 reference

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Abnormalities of insulin-like growth factor-I signaling and impaired cell proliferation in osteoblasts from subjects with osteoporosis

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Bone remodeling in post-menopausal osteoporosis

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Osteoclasts; culprits in inflammatory osteolysis

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The role of collagen in bone strength

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Estrogen and testosterone use different cellular pathways to inhibit osteoclastogenesis and bone resorption

1 reference

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Hip fracture in women without osteoporosis

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Contribution of bone mineral density and bone turnover markers to the estimation of risk of osteoporotic fracture in postmenopausal women.

1 reference

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Role of bone turnover in microdamage

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20 June 2018

Microdamage and bone strength

1 reference

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Strontium ranelate: a new paradigm in the treatment of osteoporosis.

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20 June 2018

Role of RANK ligand in mediating increased bone resorption in early postmenopausal women

1 reference

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Pros and cons of existing treatment modalities in osteoporosis: a comparison between tibolone, SERMs and estrogen (+/-progestogen) treatments.

1 reference

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Delineation of the hydroxyapatite-nucleating domains of bone sialoprotein

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Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency

1 reference

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Clinical use of bone densitometry: scientific review

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High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage

1 reference

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Alleles of RUNX2/CBFA1 gene are associated with differences in bone mineral density and risk of fracture

1 reference

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Sex steroids and the construction and conservation of the adult skeleton

1 reference

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Radiologic bone assessment in the evaluation of osteoporosis.

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Association of collagen Ialpha 1 Sp1 polymorphism with the risk of prevalent fractures: a meta-analysis.

1 reference

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Number and proliferative capacity of osteogenic stem cells are maintained during aging and in patients with osteoporosis

1 reference

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Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis

1 reference

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Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity

1 reference

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Localization of estrogen receptor beta protein expression in adult human bone.

1 reference

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TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

1 reference

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20 June 2018

Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha

1 reference

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Pathogenesis of osteoporosis

1 reference

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IGF-I and osteoporosis

1 reference

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Molecular changes in bone collagen in osteoporosis and osteoarthritis in the elderly

1 reference

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Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: increased serum concentrations in postmenopausal women with osteoporosis

1 reference

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1 reference

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Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1.

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Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin

1 reference

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Mineralisation density of human mandibular bone: quantitative backscattered electron image analysis

1 reference

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Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow. Evidence for autonomy from factors released during bone resorption

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20 June 2018

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

1 reference

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FTIR microspectroscopic analysis of human iliac crest biopsies from untreated osteoporotic bone.

1 reference

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Estrogen inhibits bone resorption by directly inducing apoptosis of the bone-resorbing osteoclasts

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Bone microdamage and skeletal fragility in osteoporotic and stress fractures

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Reduced concentration of collagen reducible cross links in human trabecular bone with respect to age and osteoporosis.

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Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I alpha 1 gene

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Nucleation of hydroxyapatite by bone sialoprotein

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Osteocytes, strain detection, bone modeling and remodeling

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Trabecular bone architecture in the pathogenesis and prevention of fracture

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Avian osteoclasts as estrogen target cells

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Candidates for the mechanosensory system in bone

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Gene expression profile of the bone microenvironment in human fragility fracture bone

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Expression characteristic and significance of interleukin-6, nuclear factor kappa beta, and bone formation markers in rat models of osteoporosis.

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26 November 2018

Production of IL-7 is increased in ovariectomized mice, but not RANKL mRNA expression by osteoblasts/stromal cells in bone, and IL-7 enhances generation of osteoclast precursors in vitro.

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26 November 2018

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26 November 2018

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26 November 2018

Bone loss dynamics result in trabecular alignment in aging and ovariectomized rats.

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26 November 2018

Stress-concentrating effect of resorption lacunae in trabecular bone.

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26 November 2018

Bone tissue material properties are altered during osteoporosis.

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26 November 2018

A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes

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26 November 2018

How many women have osteoporosis? JBMR Anniversary Classic. JBMR, Volume 7, Number 9, 1992.

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26 November 2018

Increased expression of IL-6 and RANK mRNA in human trabecular bone from fragility fracture of the femoral neck

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26 November 2018

Osteoblast-like cells from estrogen receptor alpha knockout mice have deficient responses to mechanical strain.

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26 November 2018

Microcracks: an alternative index for evaluating bone biomechanical quality

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26 November 2018

BMD at multiple sites and risk of fracture of multiple types: long-term results from the Study of Osteoporotic Fractures.

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26 November 2018

Effects of vertebral bone fragility and bone formation rate on the mineralization levels of cancellous bone from white females

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26 November 2018

Increased metabolism of bone collagen in post-menopausal female osteoporotic femoral heads

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A New Approach to the Development of Assessment Guidelines for Osteoporosis

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26 November 2018

Fracture prediction for the femoral neck using finite element models.

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26 November 2018

Does hormone-replacement therapy prevent fractures in early postmenopausal women?

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26 November 2018

Expression profiles of receptor activator of nuclear factor kappaB ligand, receptor activator of nuclear factor kappaB, and osteoprotegerin messenger RNA in aged and ovariectomized rat bones.

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26 November 2018

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26 November 2018

The burden of osteoporotic fractures: a method for setting intervention thresholds

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26 November 2018

Correlations between osteocalcin content, degree of mineralization, and mechanical properties of C. carpio rib bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Serum levels of immunoreactive bone sialoprotein in osteoporosis: positive relations to established biochemical parameters of bone turnover.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Variations in three-dimensional cancellous bone architecture of the proximal femur in female hip fractures and in controls.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Regional differences in cortical porosity in the fractured femoral neck.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Response of normal and osteoporotic human bone cells to mechanical stress in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Effect of estrogen suppression on the mineralization density of iliac crest biopsies in young women as assessed by backscattered electron imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Acute changes in trabecular bone connectivity and osteoclast activity in the ovariectomized rat in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Compositional analysis of the collagenous bone matrix. A study on adult normal and osteopenic bone tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842799

26 November 2018

Anisotropy of osteoporotic cancellous bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptor polymorphism predicts the onset of natural and surgical menopause

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of 16 weeks of treatment with tibolone on bone mass and bone mechanical and histomorphometric indices in mature ovariectomized rats with established osteopenia on a low-calcium diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The contribution of trabecular architecture to cancellous bone quality

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Associations of the collagen type Ialpha1 Sp1 polymorphism with five-year rates of bone loss in older adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does suppression of bone turnover impair mechanical properties by allowing microdamage accumulation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A physical, chemical, and mechanical study of lumbar vertebrae from normal, ovariectomized, and nandrolone decanoate-treated cynomolgus monkeys (macaca fascicularis)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoporosis changes the amount of vertebral trabecular bone at risk of fracture but not the vertebral load distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maintenance of osteoblastic and adipocytic differentiation potential with age and osteoporosis in human marrow stromal cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Study design in osteoporosis: a European perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mortality after osteoporotic fractures

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Official positions of the International Society for Clinical Densitometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered tissue properties induce changes in cancellous bone architecture in aging and diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic determinants of bone mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased osteoclast development after estrogen loss: mediation by interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NFATc1: a novel anabolic therapeutic target for osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone tissue compositional differences in women with and without osteoporotic fracture

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-linking connectivity in bone collagen fibrils: the carboxy-terminal locus of free aldehyde

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling in bone tissue of osteoporotic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancellous bone remodeling in type I (postmenopausal) osteoporosis: quantitative assessment of rates of formation, resorption, and bone loss at tissue and cellular levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural mechanisms of trabecular bone loss in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noninvasive axial and peripheral assessment of bone mineral content: a comparison between osteoporotic women and normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biophysical study of bone mineral in biopsies of osteoporotic patients before and after long-term treatment with fluoride

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of metabolic bone diseases by quantitative computed tomography

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen: the organic matrix of bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of differences in mineralization on the mechanical properties of bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The long-term skeletal effects of EHDP in dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanical properties of bone in osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen loss upregulates hematopoiesis in the mouse: a mediating role of IL-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution of soluble, mineral-bound, and matrix-bound proteins in osteoporotic and normal bones

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of gene expression in human bone biopsies by polymerase chain reaction: evidence for enhanced cytokine expression in postmenopausal osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age- and sex-related changes in iliac cortical bone mass and remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure characteristics of osteoporotic vertebral bodies monitored by acoustic emission

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovariectomy decreases the mRNA levels of transforming growth factor-beta 1 and increases the mRNA levels of osteocalcin in rat bone in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical changes in the collagen of human osteoporotic bone matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in biological activity of bone cells in ovariectomized rats revealed by in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteocyte density changes in aging and osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage colony-stimulating factor induces substantial osteoclast generation and bone resorption in human bone marrow cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in cytokine production (IL-1 beta, IL-6, TNF-alpha but not IFN-gamma, GM-CSF or LIF) by stimulated whole blood cells in postmenopausal osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A sequence variation: 713-8delC in the transforming growth factor-beta 1 gene has higher prevalence in osteoporotic women than in normal women and is associated with very low bone mass in osteoporotic women and increased bone turnover in both osteop

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration in the extent of collagen I hydroxylation, isolated from femoral heads of women with a femoral neck fracture caused by osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Material Properties of Bone from the Femoral Neck and Calcar Femorale of Patients with Osteoporosis or Osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of tibolone (Org OD14) treatment for 3 months on ovariectomy-induced osteopenia in 8-month-old rats on a low-calcium diet: preventive testing for 3 months

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of a polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to osteoporosis in postmenopausal Japanese women

1 reference

https://pubmed.ncbi.nlm.nih.gov/19846441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1098/RSIF.2009.0282

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

ResearchGate publication ID

0 references

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