(Q30476950)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

11

1 reference

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7 January 2020

Neena Kalia

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Victor Tybulewicz

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

10

Laura M Machesky

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1

Owen J T McCarty

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

3

Jocelyn M Auger

1 reference

7 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

Mark K Larson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Ben T Atkinson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Andrew C Pearce

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Sandra Ruf

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Robert B Henderson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

29 September 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

39474-39484

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

7 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1395485/fullTextXML

inferred from PubMed Central ID database lookup

cites work

WAVE/Scars in platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Cascade pathway of filopodia formation downstream of SCAR.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Rho and Rac take center stage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

α-Adducin dissociates from F-actin and spectrin during platelet activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Platelet-collagen interaction: is GPVI the central receptor?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Importance of free actin filament barbed ends for Arp2/3 complex function in platelets and fibroblasts.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Arp2/3 complex is required for actin polymerization during platelet shape change

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

The lamellipodium: where motility begins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Rho family proteins: coordinating cell responses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Comparative antiplatelet efficacy of a novel, nonpeptide GPIIb/IIIa antagonist (XV454) and abciximab (c7E3) in flow models of thrombosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Evidence that beta3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Localized Rac activation dynamics visualized in living cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Integrin-mediated signals regulated by members of the rho family of GTPases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Activation of Rac and Cdc42 by integrins mediates cell spreading

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Rho GTPases and the actin cytoskeleton

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Characterization of RAC3, a novel member of the Rho family

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Coordinated regulation of platelet actin filament barbed ends by gelsolin and capping protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

The platelet cytoskeleton stabilizes the interaction between alphaIIbbeta3 and its ligand and induces selective movements of ligand-occupied integrin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

rac, a novel ras-related family of proteins that are botulinum toxin substrates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Mechanisms of actin rearrangements mediating platelet activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Differential regulation of Rho and Rac through heterotrimeric G-proteins and cyclic nucleotides.

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504672200

Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504672200

Characterisation of Rac activation in thrombin- and collagen-stimulated human blood platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504672200

Rac, a small guanosine triphosphate-binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: roles of integrin alpha(2)beta(1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504672200

Evaluation of the role of platelet integrins in fibronectin-dependent spreading and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504672200

Differential distribution of Rac1 and Rac3 GTPases in the developing mouse brain: implications for a role of Rac3 in Purkinje cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504672200

14-3-3 zeta mediates integrin-induced activation of Cdc42 and Rac. Platelet glycoprotein Ib-IX regulates integrin-induced signaling by sequestering 14-3-3 zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504672200

GPVI levels in platelets: relationship to platelet function at high shear

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M504672200

Normal Arp2/3 complex activation in platelets lacking WASp.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1395485

Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse

26 November 2018

1 reference

12 December 2020

A Critical Role for Phospholipase Cγ2 in αIIbβ3-mediated Platelet Spreading

1 reference

12 December 2020

Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases

1 reference

12 December 2020

Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling

1 reference

12 December 2020

Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

1 reference

12 December 2020

Roles of SLP-76, phosphoinositide 3-kinase, and gelsolin in the platelet shape changes initiated by the collagen receptor GPVI/FcR gamma-chain complex

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M504672200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16195235%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

16195235

1 reference