(Q30477054)

English

Ran is required before metaphase for spindle assembly and chromosome alignment and after metaphase for chromosome segregation and spindle midbody organization

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scholarly article

1 reference

Europe PubMed Central

17 November 2017

Ran is required before metaphase for spindle assembly and chromosome alignment and after metaphase for chromosome segregation and spindle midbody organization (English)

1 reference

Europe PubMed Central

17 November 2017

author name string

Rosalind V Silverman-Gavrila

1

1 reference

Europe PubMed Central

17 November 2017

Andrew Wilde

2

1 reference

Europe PubMed Central

17 November 2017

publication date

15 February 2006

1 reference

Europe PubMed Central

17 November 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

17 November 2017

17

1 reference

Europe PubMed Central

17 November 2017

4

1 reference

Europe PubMed Central

17 November 2017

2069-2080

1 reference

Europe PubMed Central

17 November 2017

The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Crm1 is a mitotic effector of Ran-GTP in somatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

A standardized kinesin nomenclature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Mitotic functions of the Ran GTPase network: the importance of being in the right place at the right time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

The Chromokinesin, KLP3A, Drives Mitotic Spindle Pole Separation during Prometaphase and Anaphase and Facilitates Chromatid Motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

The Ran GTPase regulates kinetochore function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Mammalian RanBP1 regulates centrosome cohesion during mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Importin alpha-regulated nucleation of microtubules by TPX2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Human TPX2 is required for targeting Aurora-A kinase to the spindle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

The importin-beta P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Importin beta is a mitotic target of the small GTPase Ran in spindle assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Cytoplasmic dynein is required for poleward chromosome movement during mitosis in Drosophila embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

The role of Xgrip210 in gamma-tubulin ring complex assembly and centrosome recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Skeletor, a novel chromosomal protein that redistributes during mitosis provides evidence for the formation of a spindle matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Regulated Ran-binding protein 1 activity is required for organization and function of the mitotic spindle in mammalian cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Functional coordination of three mitotic motors in Drosophila embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

The kinesin-related protein, HSET, opposes the activity of Eg5 and cross-links microtubules in the mammalian mitotic spindle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Role of the amnioserosa in germ band retraction of the Drosophila melanogaster embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Xenopus Ran-binding protein 1: molecular interactions and effects on nuclear assembly in Xenopus egg extracts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

XMAP310: a Xenopus rescue-promoting factor localized to the mitotic spindle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

20 June 2018

Spatial coordination of spindle assembly by chromosome-mediated signaling gradients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

26 November 2018

Efficient chromosome capture requires a bias in the 'search-and-capture' process during mitotic-spindle assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

26 November 2018

Ran localizes around the microtubule spindle in vivo during mitosis in Drosophila embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

26 November 2018

Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

26 November 2018

The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

26 November 2018

Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

26 November 2018

The fusome organizes the microtubule network during oocyte differentiation in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

26 November 2018

A His2AvDGFP fusion gene complements a lethal His2AvD mutant allele and provides an in vivo marker for Drosophila chromosome behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

26 November 2018

The ran GTPase regulates mitotic spindle assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415283

26 November 2018

The role of the ran GTPase in nuclear assembly and DNA replication: characterisation of the effects of Ran mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral, non-centrosome-associated microtubules contribute to spindle formation in centrosome-containing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RanBP1 is crucial for the release of RanGTP from importin β-related nuclear transport factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new function for the gamma-tubulin ring complex as a microtubule minus-end cap

1 reference

https://pubmed.ncbi.nlm.nih.gov/16481399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E05-10-0991

1 reference

Europe PubMed Central

17 November 2017

1 reference

Europe PubMed Central

17 November 2017

1 reference

Europe PubMed Central

17 November 2017

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