(Q30479198)

English

Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease

scientific article

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scholarly article

1 reference

Europe PubMed Central

13 October 2017

Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease (English)

1 reference

Europe PubMed Central

13 October 2017

Alzheimer's disease

1 reference

based on heuristic

inferred from title

steatohepatitis

0 references

type 2 diabetes

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

non-alcoholic steatohepatitis

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

based on heuristic

inferred from title

author name string

Ming Tong

1

1 reference

Europe PubMed Central

13 October 2017

Alexander Neusner

2

1 reference

Europe PubMed Central

13 October 2017

Lisa Longato

3

1 reference

Europe PubMed Central

13 October 2017

Margot Lawton

4

1 reference

Europe PubMed Central

13 October 2017

Jack R Wands

5

1 reference

Europe PubMed Central

13 October 2017

Suzanne M de la Monte

6

1 reference

Europe PubMed Central

13 October 2017

publication date

1 January 2009

1 reference

Europe PubMed Central

13 October 2017

Journal of Alzheimer's Disease

1 reference

Europe PubMed Central

13 October 2017

17

1 reference

Europe PubMed Central

13 October 2017

827-844

1 reference

Europe PubMed Central

13 October 2017

4

1 reference

Europe PubMed Central

13 October 2017

Alzheimer's disease is type 3 diabetes-evidence reviewed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Mechanisms of nitrosamine-mediated neurodegeneration: potential relevance to sporadic Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Hepatic ceramide may mediate brain insulin resistance and neurodegeneration in type 2 diabetes and non-alcoholic steatohepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Epidemilogical trends strongly suggest exposures as etiologic agents in the pathogenesis of sporadic Alzheimer's disease, diabetes mellitus, and non-alcoholic steatohepatitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Altered lipid metabolism in brain injury and disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Free fatty acids and skeletal muscle insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Analysis of cerebellar function in Ube3a-deficient mice reveals novel genotype-specific behaviors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Evolving trends in nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Obesity, metabolic syndrome, and type 2 diabetes: inflammatory basis of glucose metabolic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Nonalcoholic fatty liver disease and mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Non-alcoholic fatty liver disease and the metabolic syndrome: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Pathology of nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Evaluation and management of obesity-related nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Insulin and insulin-like growth factor resistance with neurodegeneration in an adult chronic ethanol exposure model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Lipid mediators of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Reduced brain antioxidant capacity in rat models of betacytotoxic-induced experimental sporadic Alzheimer's disease and diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Role of mitochondria in non-alcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Metabolic syndrome and NASH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Update on non-alcoholic fatty liver disease in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Next steps in Alzheimer's disease research: interaction between epidemiology and basic science

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Diabetes mellitus and dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Nonalcoholic steatohepatitis--a histological perspective.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Chronic gestational exposure to ethanol causes insulin and IGF resistance and impairs acetylcholine homeostasis in the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Ceramides in insulin resistance and lipotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

The clinical and biological relationship between Type II diabetes mellitus and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Causes and consequences of disturbances of cerebral glucose metabolism in sporadic Alzheimer disease: therapeutic implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Genotoxicity of streptozotocin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Radicals and oxidative stress in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Inhibition of the neuronal insulin receptor causes Alzheimer-like disturbances in oxidative/energy brain metabolism and in behavior in adult rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Site-specific DNA methylation and apoptosis: induction by diabetogenic streptozotocin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Disruption of spatial but not object-recognition memory by neurotoxic lesions of the dorsal hippocampus in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Evidence for multiple causality in the development of diabetic hypertriglyceridaemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Induction of carcinogenesis in Fischer rats by methylalkylnitrosamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

N-nitrosamines in the stomach with special reference to in vitro formation, and kinetics after intragastric or intravenous administration in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Studies on the Mechanism of the Diabetogenic Activity of Streptozotocin and on the Ability of Compounds to Block the Diabetogenic Activity of Streptozotocin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

Studies of streptozotocin-induced insulitis and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

20 June 2018

The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Gene expression alterations in brain areas of intracerebroventricular streptozotocin treated rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Rodent nutritional model of steatohepatitis: effects of endotoxin (lipopolysaccharide) and tumor necrosis factor alpha deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Induction of macrophage scavenger receptor MARCO in nonalcoholic steatohepatitis indicates possible involvement of endotoxin in its pathogenic process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Corticohippocampal contributions to spatial and contextual learning.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Comparative immunocytochemistry of isolated rat & monkey pancreatic islet cell types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: potential strategies for neuroprotection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Inhibition of the neuronal insulin receptor. An in vivo model for sporadic Alzheimer disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Characterization of perforant path lesions in rodent models of memory and attention.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Use of the Morris water maze and acoustic startle chamber to evaluate neurologic injury after asphyxial arrest in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

The rotarod test: an evaluation of its effectiveness in assessing motor deficits following traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Pancreatic islet hypertrophy in spontaneous maturity onset obese-diabetic CBA/Ca mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952429

26 November 2018

High sensitivity of fatty liver Shionogi (FLS) mice to diethylnitrosamine hepatocarcinogenesis: comparison to C3H and C57 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diethylnitrosamine oncogenesis in RF mice as influenced by variations in cumulative dose

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liposolubility as an aspect of nitrosamine carcinogenicity: Quantitative correlations and qualitative observations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose response studies of carcinogenesis in rats by nitrosodiethylamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement by streptozotocin of O2- radical generation by the xanthine oxidase system of pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of N-nitrosomethylaniline

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lethal forebrain ischemia stimulates sphingomyelin hydrolysis and ceramide generation in the gerbil hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological activity of urease formulated in poloxamer 407 after intraperitoneal injection in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetic complications in a new animal model (TSOD mouse) of spontaneous NIDDM with obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage induced by seven N-nitroso compounds in primary cultures of human and rat kidney cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20387270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

13 October 2017

1 reference

Europe PubMed Central

13 October 2017

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