(Q30481799)

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Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction (English)

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Phospholipase A2 group IVA

1 reference

GOA release 2020-03-11

calcium-dependent phospholipase A2 activity

1 reference

GOA release 2020-03-11

Ginger Lohr Milne

5

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

David A. Brenner

object named as

David A Brenner

8

0 references

11

object named as

John A Oates

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Olivier Boutaud

10

object named as

Olivier Boutaud

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

author name string

David H Adler

1

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Joy D Cogan

2

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

John A Phillips

3

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Nathalie Schnetz-Boutaud

4

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Tina Iverson

6

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Jeffrey A Stein

7

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Jason D Morrow

9

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

language of work or name

0 references

publication date

1 June 2008

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

118

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

6

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

2121-2131

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Intracellular actions of group IIA secreted phospholipase A2 and group IVA cytosolic phospholipase A2 contribute to arachidonic acid release and prostaglandin production in rat gastric mucosal cells and transfected human embryonic kidney cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Low-dose aspirin for the prevention of atherothrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Diverse cellular localizations of secretory phospholipase A2 enzymes in several human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

The role of prostaglandins and other eicosanoids in the gastrointestinal tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Non-specific multiple ulcers of the small intestine unrelated to non-steroidal anti-inflammatory drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Raster3D Version 2.0. A program for photorealistic molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Cytosolic phospholipase A2alpha reigns supreme in arthritis and bone resorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Wireless capsule endoscopy detects small bowel ulcers in patients with normal results from state of the art enteroclysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Discrete role for cytosolic phospholipase A(2)alpha in platelets: studies using single and double mutant mice of cytosolic and group IIA secretory phospholipase A(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Roles of catalytic domain residues in interfacial binding and activation of group IV cytosolic phospholipase A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Association between aspirin and upper gastrointestinal complications: systematic review of epidemiologic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Specific physiological roles of cytosolic phospholipase A(2) as defined by gene knockouts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Structure and mechanism of human cytosolic phospholipase A(2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Role of phosphorylation sites and the C2 domain in regulation of cytosolic phospholipase A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Crystal structure of human cytosolic phospholipase A2 reveals a novel topology and catalytic mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

The 85-kD cytosolic phospholipase A2 knockout mouse: a new tool for physiology and cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Group IV cytosolic phospholipase A2 binds with high affinity and specificity to phosphatidylinositol 4,5-bisphosphate resulting in dramatic increases in activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Properties and regulation of cytosolic phospholipase A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Simplified assay for the quantification of 2,3-dinor-6-keto-prostaglandin F1 alpha by gas chromatography-mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Cytosolic phospholipase A2 gene in human and rat: chromosomal localization and polymorphic markers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Indomethacin-induced intestinal lesions in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Identification and characterization of a hormonally regulated form of phospholipase A2 in rat renal mesangial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Thromboxane A2 biosynthesis in human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

20 June 2018

Separation and identification of F2-isoprostane regioisomers and diastereomers by novel liquid chromatographic/mass spectrometric methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE2 synthesis in healthy humans and those with lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

Interactions of 12-lipoxygenase with phospholipase A2 isoforms following platelet activation through the glycoprotein VI collagen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

Assaying phospholipase A2 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

Mechanism of group IVA cytosolic phospholipase A(2) activation by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

Deletion of cytosolic phospholipase A2 promotes striated muscle growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

Translocation of cytosolic phospholipase A2 to the nuclear envelope elicits topographically localized phospholipid hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2350426

26 November 2018

Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin-induced phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splicing mutation of the prostacyclin synthase gene in a family associated with hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conditions influencing release of granule contents from human platelets in citrated plasma induced by ADP or the thrombin receptor activating peptide SFLLRN: direct measurement of percent release of beta-thromboglobulin and assessment by flow cytome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-mediated translocation of cytosolic phospholipase A2 to the nuclear envelope and endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved assay for the quantification of 11-dehydrothromboxane B2 by gas chromatography-mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interrelationship between thromboxane biosynthesis, aggregation and 5-hydroxytryptamine secretion in human platelets in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of leukotriene E4 in human urine using liquid chromatography-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tight binding inhibitors of 85-kDa phospholipase A2 but not 14-kDa phospholipase A2 inhibit release of free arachidonate in thrombin-stimulated human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indomethacin-induced lesion modifies contractile activity in rat small intestines

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by leukotriene inhibitors, and calcium and platelet-activating factor antagonists, of acute gastric and intestinal damage in arthritic rats and in cholinomimetic-treated mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18451993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI30473

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

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