(Q30484892)

17 August 2017

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear (English)

1 reference

17 August 2017

11

Hannah Monyer

1 reference

17 August 2017

Fabio Mammano

12

1 reference

ORCID Public Data File 2021

author name string

Fabio Anselmi

1

1 reference

17 August 2017

Victor H Hernandez

2

1 reference

17 August 2017

Giulia Crispino

3

1 reference

17 August 2017

Anke Seydel

4

1 reference

17 August 2017

Saida Ortolano

5

1 reference

17 August 2017

Stephen D Roper

6

1 reference

17 August 2017

Nicoletta Kessaris

7

1 reference

17 August 2017

William Richardson

8

1 reference

17 August 2017

Gesa Rickheit

9

1 reference

17 August 2017

Mikhail A Filippov

10

1 reference

17 August 2017

language of work or name

English

0 references

publication date

1 December 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

17 August 2017

1 reference

17 August 2017

105

1 reference

17 August 2017

48

1 reference

17 August 2017

18770-18775

1 reference

Connexin 43 hemichannels are permeable to ATP.

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Pannexins and gap junction protein diversity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Pannexin1 channels contain a glycosylation site that targets the hexamer to the plasma membrane

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

A novel mechanism for connexin 26 mutation linked deafness: cell death caused by leaky gap junction hemichannels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Species specificity of mammalian connexin-26 to form open voltage-gated hemichannels.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Functional connexin “hemichannels”: A critical appraisal

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Astrocyte calcium waves: what they are and what they do.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Calcium signaling in specialized glial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Molecular and physiological bases of the K+ circulation in the mammalian inner ear.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Supporting sensory transduction: cochlear fluid homeostasis and the endocochlear potential

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Gap junctions and cochlear homeostasis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Pannexin 1 in erythrocytes: function without a gap

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Heteromeric, but not homomeric, connexin channels are selectively permeable to inositol phosphates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Cell-cell communication beyond connexins: the pannexin channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Regulation of connexin hemichannels by monovalent cations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Intracellular calcium changes trigger connexin 32 hemichannel opening

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Connexin-based gap junction hemichannels: gating mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Cochlear gap junctions coassembled from Cx26 and 30 show faster intercellular Ca2+ signaling than homomeric counterparts.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Pannexin membrane channels are mechanosensitive conduits for ATP

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Noise exposure induces up-regulation of ecto-nucleoside triphosphate diphosphohydrolases 1 and 2 in rat cochlea

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

New roles for astrocytes: Gap junction hemichannels have something to communicate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Pharmacological sensitivity of ATP release triggered by photoliberation of inositol-1,4,5-trisphosphate and zero extracellular calcium in brain endothelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Gating and regulation of connexin 43 (Cx43) hemichannels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Permeability and gating properties of human connexins 26 and 30 expressed in HeLa cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Beyond the gap: functions of unpaired connexon channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

ATP-gated ion channels assembled from P2X2 receptor subunits in the mouse cochlea.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Vesicular storage of adenosine triphosphate in the guinea-pig cochlear lateral wall and concentrations of ATP in the endolymph during sound exposure and hypoxia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Purinergic control of intercellular communication between Hensen's cells of the guinea-pig cochlea

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Intercellular calcium signaling and flash photolysis of caged compounds. A sensitive method to evaluate gap junctional coupling.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Defective propagation of signals generated by sympathetic nerve stimulation in the liver of connexin32-deficient mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Very low calcium content of cochlear endolymph, an extracellular fluid

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Concentration of MgATP2- and other ions in solution. Calculation of the true concentrations of species present in mixtures of associating ions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Glial fibrillary acidic protein expression and promoter activity in the inner ear of developing and adult mice.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

A mechanism for sensing noise damage in the inner ear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

Impaired permeability to Ins(1,4,5)P3 in a mutant connexin underlies recessive hereditary deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

ATP released via gap junction hemichannels from the pigment epithelium regulates neural retinal progenitor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

Connexin-dependent inter-cellular communication increases invasion and dissemination of Shigella in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

Connexin30 mutations responsible for hidrotic ectodermal dysplasia cause abnormal hemichannel activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

Expression of the P2X7 receptor subunit of the adenosine 5'-triphosphate-gated ion channel in the developing and adult rat cochlea

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

Modulation of membrane channel currents by gap junction protein mimetic peptides: size matters

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

Purinergic regulation of sound transduction and auditory neurotransmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

Compartmentalized and signal-selective gap junctional coupling in the hearing cochlea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

P2X7 purinoceptor expression in Xenopus oocytes is not sufficient to produce a pore-forming P2Z-like phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

The origin of spontaneous activity in the developing auditory system.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596208

Purinergic signalling and intercellular Ca2+ wave propagation in the organ of Corti

26 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800793105

Unitary permeability of gap junction channels to second messengers measured by FRET microscopy

21 January 2018

1 reference

12 December 2020

Extracellular-loop peptide antibodies reveal a predominant hemichannel organization of connexins in polarized intestinal cells

1 reference

12 December 2020

Electrical properties of gap junction hemichannels identified in transfected HeLa cells

1 reference

12 December 2020

A fluorescence photobleaching assay of gap junction-mediated communication between human cells

1 reference

12 December 2020

Calcium waves in astrocytes-filling in the gaps

1 reference

12 December 2020

Quinacrine staining of marginal cells in the stria vascularis of the guinea-pig cochlea: a possible source of extracellular ATP?

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0800793105

1 reference

17 August 2017

0 references

1 reference

17 August 2017

1 reference