(Q30487845)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Eva Cuypers

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Dirk J Snyders

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

6

Jan Tytgat

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Alain J Labro

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Henry W B Johnson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Jon D Rainier

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

29 May 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

9896-9901

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

The continuing saga of the marine polyether biotoxins

29 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Physiology and pathophysiology of potassium channels in gastrointestinal epithelia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Tarantula toxins interact with voltage sensors within lipid membranes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Closing in on the resting state of the Shaker K(+) channel.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

The molecular basis of high-affinity binding of the antiarrhythmic compound vernakalant (RSD1235) to Kv1.5 channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Gambierol acts as a functional antagonist of neurotoxin site 5 on voltage-gated sodium channels in cerebellar granule neurons

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Voltage-gated ion channels and gating modifier toxins.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Tarantula toxins interacting with voltage sensors in potassium channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Voltage-sensor activation with a tarantula toxin as cargo.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Inhibition of voltage-gated potassium currents by gambierol in mouse taste cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Novel interactions between K+ channels and scorpion toxins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Inhibition of brevetoxin binding to the voltage-gated sodium channel by gambierol and gambieric acid-A.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

VMD: visual molecular dynamics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

High affinity open channel block by dofetilide of HERG expressed in a human cell line.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Revealing the architecture of a K+ channel pore through mutant cycles with a peptide inhibitor.

14 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812471106

The alpha-dendrotoxin footprint on a mammalian potassium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812471106

Structural basis of TEA blockade in a model potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812471106

Binding site of a novel Kv1.5 blocker: a "foot in the door" against atrial fibrillation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812471106

Block of voltage-gated potassium channels by Pacific ciguatoxin-1 contributes to increased neuronal excitability in rat sensory neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812471106

Diverted Total Synthesis and Biological Evaluation of Gambierol Analogues: Elucidation of Crucial Structural Elements for Potent Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812471106

A single residue in the S6 transmembrane domain governs the differential flecainide sensitivity of voltage-gated potassium channels

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688436

Identification of peptide components of the brevetoxin receptor site of rat brain sodium channels

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19482941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Total synthesis of gambierol: subunit coupling and completion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19482941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0812471106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482941%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

19482941

1 reference