(Q30489530)

22 June 2017

Large-scale phenome analysis defines a behavioral signature for Huntington's disease genotype in mice (English)

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22 June 2017

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22

James F Gusella

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22 June 2017

23

Marcy E MacDonald

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22 June 2017

19

Vanessa C Wheeler

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22 June 2017

25

Seung Kwak

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22 June 2017

Vadim Alexandrov

1

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22 June 2017

Dani Brunner

2

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22 June 2017

Liliana B Menalled

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22 June 2017

Andrea Kudwa

4

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22 June 2017

Judy Watson-Johnson

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22 June 2017

Matthew Mazzella

6

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22 June 2017

Ian Russell

7

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22 June 2017

Melinda C Ruiz

8

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22 June 2017

Justin Torello

9

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22 June 2017

Emily Sabath

10

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22 June 2017

Ana Sanchez

11

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22 June 2017

Miguel Gomez

12

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22 June 2017

Igor Filipov

13

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22 June 2017

Kimberly Cox

14

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22 June 2017

Mei Kwan

15

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22 June 2017

Afshin Ghavami

16

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22 June 2017

Sylvie Ramboz

17

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22 June 2017

Brenda Lager

18

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22 June 2017

Jeff Aaronson

20

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22 June 2017

Jim Rosinski

21

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22 June 2017

David Howland

24

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22 June 2017

4 July 2016

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22 June 2017

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22 June 2017

34

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22 June 2017

8

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22 June 2017

838-844

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Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

22 June 2017

1 reference

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches

21 January 2018

1 reference

Mutation size and age at onset in Huntington's disease

21 January 2018

1 reference

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.

21 January 2018

1 reference

Studies on neurotransmitter markers and striatal neuronal cell density in Huntington's disease and dentatorubropallidoluysian atrophy

21 January 2018

1 reference

21 January 2018

Mouse ENU mutagenesis

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DRPLA transgenic mouse substrains carrying single copy of full-length mutant human DRPLA gene with variable sizes of expanded CAG repeats exhibit CAG repeat length- and age-dependent changes in behavioral abnormalities and gene expression profiles.

21 January 2018

1 reference

Behavioral signatures related to genetic disorders in autism

21 January 2018

1 reference

High-throughput analysis of behavior for drug discovery

21 January 2018

1 reference

Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.

21 January 2018

1 reference

21 January 2018

1 reference

Huntington disease in a 9-year-old boy: clinical course and neuropathologic examination

21 January 2018

1 reference

21 January 2018

1 reference

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

21 January 2018

1 reference

Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.

21 January 2018

1 reference

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

21 January 2018

1 reference

CAG repeat lengths > or =335 attenuate the phenotype in the R6/2 Huntington's disease transgenic mouse

21 January 2018

1 reference

Early onset deficits on the delayed alternation task in the Hdh(Q92) knock-in mouse model of Huntington's disease.

21 January 2018

1 reference

Rule learning, visuospatial function and motor performance in the Hdh(Q92) knock-in mouse model of Huntington's disease.

21 January 2018

1 reference

Time course of choice reaction time deficits in the Hdh(Q92) knock-in mouse model of Huntington's disease in the operant serial implicit learning task (SILT).

21 January 2018

1 reference

Longitudinal analysis of the behavioural phenotype in HdhQ92 Huntington's disease knock-in mice

21 January 2018

1 reference

Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods

21 January 2018

1 reference

Rapid, computer vision-enabled murine screening system identifies neuropharmacological potential of two new mechanisms

21 January 2018

1 reference

Systemic administration of Congo red does not improve motor or cognitive function in R6/2 mice.

21 January 2018

1 reference

Comparative psychology and the grand challenge of drug discovery in psychiatry and neurodegeneration

21 January 2018

1 reference

Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline

21 January 2018

1 reference

A patient with Huntington's disease and long-surviving fetal neural transplants that developed mass lesions

21 January 2018

1 reference

Huntington's disease is a disorder of the corpus striatum: focus on Rhes (Ras homologue enriched in the striatum).

21 January 2018

1 reference

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

21 January 2018

1 reference

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease

21 January 2018

1 reference

Endogenous kynurenines as targets for drug discovery and development

21 January 2018

1 reference

Human disease-drug network based on genomic expression profiles

21 January 2018

1 reference

Circadian Abnormalities in Motor Activity in a BAC Transgenic Mouse Model of Huntington's Disease

21 January 2018

1 reference

12 December 2020

A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease

1 reference

12 December 2020

Randomized controlled trial of ethyl-eicosapentaenoic acid in Huntington disease: the TREND-HD study

1 reference

12 December 2020

Cognitive deficits in transgenic and knock-in HTT mice parallel those in Huntington's disease

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12 December 2020

High-Throughput Automated Phenotyping of Two Genetic Mouse Models of Huntington's Disease

1 reference

12 December 2020

Multivariate assessment of locomotor behavior: pharmacological and behavioral analyses

1 reference

12 December 2020

A mixed fixed ratio/progressive ratio procedure reveals an apathy phenotype in the BAC HD and the z_Q175 KI mouse models of Huntington's disease

1 reference

12 December 2020

The rise and fall of Dimebon

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12 December 2020

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NBT.3587

1 reference

22 June 2017

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