(Q30492865)

English

Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease

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scholarly article

1 reference

Europe PubMed Central

16 October 2017

Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease (English)

1 reference

Europe PubMed Central

16 October 2017

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object named as

Andreas Schedl

9

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object named as

Anne Joutel

1

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author name string

Marie Monet-Leprêtre

2

1 reference

Europe PubMed Central

16 October 2017

Claudia Gosele

3

1 reference

Europe PubMed Central

16 October 2017

Céline Baron-Menguy

4

1 reference

Europe PubMed Central

16 October 2017

Annette Hammes

5

1 reference

Europe PubMed Central

16 October 2017

Sabine Schmidt

6

1 reference

Europe PubMed Central

16 October 2017

Barbara Lemaire-Carrette

7

1 reference

Europe PubMed Central

16 October 2017

Valérie Domenga

8

1 reference

Europe PubMed Central

16 October 2017

Pierre Lacombe

10

1 reference

Europe PubMed Central

16 October 2017

Norbert Hubner

11

1 reference

Europe PubMed Central

16 October 2017

language of work or name

0 references

publication date

11 January 2010

1 reference

Europe PubMed Central

16 October 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

16 October 2017

120

1 reference

Europe PubMed Central

16 October 2017

433-445

1 reference

Europe PubMed Central

16 October 2017

2

1 reference

Europe PubMed Central

16 October 2017

1 reference

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14 July 2018

Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Notch3 is a major regulator of vascular tone in cerebral and tail resistance arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review.

1 reference

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14 July 2018

The blood-brain barrier in health and chronic neurodegenerative disorders

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14 July 2018

Genes, endothelial function and cerebral small vessel disease in man.

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14 July 2018

The enigma of vascular cognitive disorder and vascular dementia

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14 July 2018

Genetics of ischaemic stroke

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

DNER acts as a neuron-specific Notch ligand during Bergmann glial development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Impaired cerebral vasoreactivity in a transgenic mouse model of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy arteriopathy

1 reference

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14 July 2018

Cerebral small vessel diseases: cerebral microangiopathies

1 reference

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14 July 2018

Notch3 is required for arterial identity and maturation of vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Long-term prognosis and causes of death in CADASIL: a retrospective study in 411 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

CADASIL-associated Notch3 mutations have differential effects both on ligand binding and ligand-induced Notch3 receptor signaling through RBP-Jk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Neurovascular regulation in the normal brain and in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Pathogenic mutations associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy differently affect Jagged1 binding and Notch3 activity via the RBP/JK signaling Pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Skin biopsy immunostaining with a Notch3 monoclonal antibody for CADASIL diagnosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Modular bacterial artificial chromosome vectors for transfer of large inserts into mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Cerebral hemodynamics in CADASIL before and after acetazolamide challenge assessed with MRI bolus tracking.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Postmortem diffusion of autoradiographic blood flow tracers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

CADASIL: hereditary disease of arteries causing brain infarcts and dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Patterns of MRI lesions in CADASIL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Construction and characterization of a 10-fold genome equivalent rat P1-derived artificial chromosome library

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

CADASIL: skin biopsy allows diagnosis in early stages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Pathogenesis of leukoaraiosis: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

The SM 22 promoter directs tissue-specific expression in arterial but not in venous or visceral smooth muscle cells in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Transcriptional regulation of multigene loci: multilevel control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Systemic vascular smooth muscle cell impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

Measurement of local cerebral blood flow with [14C]iodoantipyrine in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

14 July 2018

The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

26 November 2018

Notch3 ectodomain is a major component of granular osmiophilic material (GOM) in CADASIL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

26 November 2018

Reduced brain tissue perfusion in TGF-beta 1 transgenic mice showing Alzheimer's disease-like cerebrovascular abnormalities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

26 November 2018

Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

26 November 2018

Positron emission tomography examination of cerebral blood flow and glucose metabolism in young CADASIL patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

26 November 2018

Long-term measurement of cerebral blood flow and metabolism in a rat chronic hypoperfusion model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

26 November 2018

Patterns of cerebral blood flow reduction in patients with ischemic leukoaraiosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

26 November 2018

SPECT study of a German CADASIL family: a phenotype with migraine and progressive dementia only.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

26 November 2018

Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810078

26 November 2018

The phenotypic spectrum of CADASIL: clinical findings in 102 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20071773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrosis and stenosis of the long penetrating cerebral arteries: the cause of the white matter pathology in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20071773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectrum of mutations in biopsy-proven CADASIL: implications for diagnostic strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20071773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manipulating large insert clones for transgenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20071773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI39733

1 reference

Europe PubMed Central

16 October 2017

1 reference

Europe PubMed Central

16 October 2017

1 reference

Europe PubMed Central

16 October 2017

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