(Q30493280)

19 October 2017

Toxoplasma gondii actin depolymerizing factor acts primarily to sequester G-actin (English)

1 reference

19 October 2017

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2

L David Sibley

1 reference

19 October 2017

Simren Mehta

1

1 reference

PMCID

2825477

19 October 2017

language of work or name

English

0 references

publication date

30 December 2009

1 reference

Journal of Biological Chemistry

19 October 2017

1 reference

19 October 2017

285

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19 October 2017

6835-6847

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19 October 2017

9

1 reference

PMCID

2825477

describes a project that uses

19 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2825477/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Essential role of ADF/cofilin for assembly of contractile actin networks in the C. elegans somatic gonad

14 July 2018

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A malaria parasite formin regulates actin polymerization and localizes to the parasite-erythrocyte moving junction during invasion

14 July 2018

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Toxoplasma profilin is essential for host cell invasion and TLR11-dependent induction of an interleukin-12 response.

14 July 2018

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14 July 2018

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Regulation of apicomplexan microfilament dynamics by a minimal set of actin-binding proteins

14 July 2018

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Regulation of apicomplexan actin-based motility

14 July 2018

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Unusual kinetic and structural properties control rapid assembly and turnover of actin in the parasite Toxoplasma gondii

14 July 2018

1 reference

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The two Caenorhabditis elegans actin-depolymerizing factor/cofilin proteins differently enhance actin filament severing and depolymerization

14 July 2018

1 reference

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A Plasmodium actin-depolymerizing factor that binds exclusively to actin monomers

14 July 2018

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Unusual properties of Plasmodium falciparum actin: new insights into microfilament dynamics of apicomplexan parasites

14 July 2018

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Real-time measurements of actin filament polymerization by total internal reflection fluorescence microscopy

14 July 2018

1 reference

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Intracellular parasite invasion strategies

14 July 2018

1 reference

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Migration of Toxoplasma gondii across biological barriers

14 July 2018

1 reference

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Actin binding proteins: regulation of cytoskeletal microfilaments

14 July 2018

1 reference

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Actin filament polymerization regulates gliding motility by apicomplexan parasites

14 July 2018

1 reference

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Mapping the G-actin binding surface of cofilin using synchrotron protein footprinting

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Direct real-time observation of actin filament branching mediated by Arp2/3 complex using total internal reflection fluorescence microscopy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Intracellular pH modulation of ADF/cofilin proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

The C-terminal tail of UNC-60B (actin depolymerizing factor/cofilin) is critical for maintaining its stable association with F-actin and is implicated in the second actin-binding site.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

A comparative structural analysis of the ADF/cofilin family

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Molecular mechanisms controlling actin filament dynamics in nonmuscle cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Proteins of the ADF/cofilin family: essential regulators of actin dynamics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Two activities of cofilin, severing and accelerating directional depolymerization of actin filaments, are affected differentially by mutations around the actin-binding helix

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Time-lapse video microscopy of gliding motility in Toxoplasma gondii reveals a novel, biphasic mechanism of cell locomotion

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Induction of an acrosomal process in Toxoplasma gondii: visualization of actin filaments in a protozoan parasite

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

UNC-60B, an ADF/cofilin family protein, is required for proper assembly of actin into myofibrils in Caenorhabditis elegans body wall muscle

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Interaction of actin monomers with Acanthamoeba actophorin (ADF/cofilin) and profilin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Essential functions and actin-binding surfaces of yeast cofilin revealed by systematic mutagenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Cloning and characterization of actin depolymerizing factor from Toxoplasma gondii

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Cofilin changes the twist of F-actin: implications for actin filament dynamics and cellular function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Actin in the parasite Toxoplasma gondii is encoded by a single copy gene, ACT1 and exists primarily in a globular form.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Cofilin promotes rapid actin filament turnover in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Crystal structure of the actin-binding protein actophorin from Acanthamoeba

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Structure determination of yeast cofilin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Phosphorylation of Ser-3 of cofilin regulates its essential function on actin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Tertiary structure of destrin and structural similarity between two actin-regulating protein families

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Small actin-binding proteins: the beta-thymosin family

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Primary structure of and studies on Acanthamoeba actophorin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Partial purification and characterization of an actin depolymerizing factor from brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

An actin-depolymerizing protein (depactin) from starfish oocytes: properties and interaction with actin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Opposite effects of cofilin and profilin from porcine brain on rate of exchange of actin-bound adenosine 5'-triphosphate.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

pH control of actin polymerization by cofilin.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Actin concentration and monomer-polymer ratio in developing chicken skeletal muscle

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Inhibition of actin polymerization by a synthetic dodecapeptide patterned on the sequence around the actin-binding site of cofilin.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Mutational analysis of an actin-binding site of cofilin and characterization of chimeric proteins between cofilin and destrin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Biochemistry of actomyosin-dependent cell motility (a review)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Cofilin dissociates Arp2/3 complex and branches from actin filaments

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Mechanism of actin filament turnover by severing and nucleation at different concentrations of ADF/cofilin.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Malaria parasite actin filaments are very short

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

In vitro activity differences between proteins of the ADF/cofilin family define two distinct subgroups.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Specific requirement for two ADF/cofilin isoforms in distinct actin-dependent processes in Caenorhabditis elegans.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Phosphorylation of Acanthamoeba actophorin (ADF/cofilin) blocks interaction with actin without a change in atomic structure

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Kinetic analysis of the interaction of actin-depolymerizing factor (ADF)/cofilin with G- and F-actins. Comparison of plant and human ADFs and effect of phosphorylation.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

Ser6 in the maize actin-depolymerizing factor, ZmADF3, is phosphorylated by a calcium-stimulated protein kinase and is essential for the control of functional activity.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825477

The effect of two actin depolymerizing factors (ADF/cofilins) on actin filament turnover : pH sensitivity of F-actin binding by human ADF, but not of Acanthamoeba actophorin

26 November 2018

1 reference

12 December 2020

Characterization and expression of an actin-depolymerizing factor from Eimeria tenella

1 reference

12 December 2020

Usual and unusual biochemical properties of ADF/cofilin-like protein Adf73p in ciliate Tetrahymena thermophila

1 reference

12 December 2020

Toxoplasma gondii motility and host cell invasiveness are drastically impaired by jasplakinolide, a cyclic peptide stabilizing F-actin

1 reference

12 December 2020

Uncoupling actin filament fragmentation by cofilin from increased subunit turnover

1 reference

12 December 2020

Actin filament disassembly in blood plasma

1 reference

12 December 2020

An actin-depolymerizing protein (destrin) from porcine kidney. Its action on F-actin containing or lacking tropomyosin

1 reference

12 December 2020

An actin-depolymerizing protein in embryonic chicken skeletal muscle: purification and characterization

1 reference

12 December 2020

Analysis of the interactions of actin depolymerizing factor with G- and F-actin

1 reference

12 December 2020

Reactivation of phosphorylated actin depolymerizing factor and identification of the regulatory site

1 reference

12 December 2020

Two Caenorhabditis elegans actin depolymerizing factor/cofilin proteins, encoded by the unc-60 gene, differentially regulate actin filament dynamics

1 reference

12 December 2020

How ADF/cofilin depolymerizes actin filaments

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.068155

1 reference

19 October 2017

1 reference

19 October 2017

1 reference

PMCID

2825477