(Q30494926)

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Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiae

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scholarly article

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Europe PubMed Central

14 November 2017

Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiae (English)

1 reference

Europe PubMed Central

14 November 2017

Saccharomyces cerevisiae

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Bernd Nidetzky

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author name string

Barbara Petschacher

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1 reference

Europe PubMed Central

14 November 2017

publication date

17 March 2008

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Europe PubMed Central

14 November 2017

Microbial Cell Factories

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Europe PubMed Central

14 November 2017

7

1 reference

Europe PubMed Central

14 November 2017

9

1 reference

Europe PubMed Central

14 November 2017

https://scigraph.springernature.com/pub.10.1186/1475-2859-7-9

0 references

Development of efficient xylose fermentation in Saccharomyces cerevisiae: xylose isomerase as a key component.

1 reference

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28 July 2018

Metabolic engineering for pentose utilization in Saccharomyces cerevisiae

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Fueling industrial biotechnology growth with bioethanol

1 reference

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28 July 2018

Genetic improvement of Saccharomyces cerevisiae for xylose fermentation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Towards industrial pentose-fermenting yeast strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Comparison of the xylose reductase-xylitol dehydrogenase and the xylose isomerase pathways for xylose fermentation by recombinant Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Structural and kinetic studies of induced fit in xylulose kinase from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Bio-ethanol--the fuel of tomorrow from the residues of today

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Alcoholic fermentation of carbon sources in biomass hydrolysates by Saccharomyces cerevisiae: current status.

1 reference

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28 July 2018

Engineering yeasts for xylose metabolism

1 reference

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28 July 2018

Co-utilization of L-arabinose and D-xylose by laboratory and industrial Saccharomyces cerevisiae strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Engineering Candida tenuis Xylose reductase for improved utilization of NADH: antagonistic effects of multiple side chain replacements and performance of site-directed mutants under simulated in vivo conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Metabolic engineering of a phosphoketolase pathway for pentose catabolism in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Engineering redox cofactor regeneration for improved pentose fermentation in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Metabolic engineering of ammonium assimilation in xylose-fermenting Saccharomyces cerevisiae improves ethanol production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

A modified Saccharomyces cerevisiae strain that consumes L-Arabinose and produces ethanol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Reduced oxidative pentose phosphate pathway flux in recombinant xylose-utilizing Saccharomyces cerevisiae strains improves the ethanol yield from xylose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Anaerobic xylose fermentation by recombinant Saccharomyces cerevisiae carrying XYL1, XYL2, and XKS1 in mineral medium chemostat cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Metabolic engineering applications to renewable resource utilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Xylose utilisation: cloning and characterisation of the xylitol dehydrogenase from Galactocandida mastotermitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Xylose utilisation: cloning and characterisation of the Xylose reductase from Candida tenuis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Structural and functional properties of a yeast xylitol dehydrogenase, a Zn2+-containing metalloenzyme similar to medium-chain sorbitol dehydrogenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Genetically engineered Saccharomyces yeast capable of effective cofermentation of glucose and xylose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

NAD(P)H-dependent aldose reductase from the xylose-assimilating yeast Candida tenuis. Isolation, characterization and biochemical properties of the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Ethanolic fermentation of xylose with Saccharomyces cerevisiae harboring the Thermus thermophilus xylA gene, which expresses an active xylose (glucose) isomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

A super-family of medium-chain dehydrogenases/reductases (MDR). Sub-lines including zeta-crystallin, alcohol and polyol dehydrogenases, quinone oxidoreductase enoyl reductases, VAT-1 and other proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Short-chain dehydrogenases/reductases (SDR)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds

1 reference

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28 July 2018

Properties of the NAD(P)H-dependent xylose reductase from the xylose-fermenting yeast Pichia stipitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Isolation and characterization of the Pichia stipitis xylitol dehydrogenase gene, XYL2, and construction of a xylose-utilizing Saccharomyces cerevisiae transformant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

28 July 2018

Production of ethanol from L-arabinose by Saccharomyces cerevisiae containing a fungal L-arabinose pathway

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Production of ethanol from cellulosic biomass hydrolysates using genetically engineered Saccharomyces yeast capable of cofermenting glucose and xylose

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Conversion of xylose to ethanol by recombinant Saccharomyces cerevisiae: importance of xylulokinase (XKS1) and oxygen availability

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Ethanol production from xylose by recombinant Saccharomyces cerevisiae expressing protein-engineered NADH-preferring xylose reductase from Pichia stipitis.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

The positive effect of the decreased NADPH-preferring activity of xylose reductase from Pichia stipitis on ethanol production using xylose-fermenting recombinant Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Effect of the reversal of coenzyme specificity by expression of mutated Pichia stipitis xylitol dehydrogenase in recombinant Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Ethanol production from xylose by recombinant Saccharomyces cerevisiae expressing protein engineered NADP+-dependent xylitol dehydrogenase.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Complete reversal of coenzyme specificity of xylitol dehydrogenase and increase of thermostability by the introduction of structural zinc

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

High-level functional expression of a fungal xylose isomerase: the key to efficient ethanolic fermentation of xylose by Saccharomyces cerevisiae?

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Metabolic engineering of a xylose-isomerase-expressing Saccharomyces cerevisiae strain for rapid anaerobic xylose fermentation

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Evolutionary engineering of mixed-sugar utilization by a xylose-fermenting Saccharomyces cerevisiae strain

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Minimal metabolic engineering of Saccharomyces cerevisiae for efficient anaerobic xylose fermentation: a proof of principle

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Variations and constant patterns in eukaryotic MDR enzymes. Conclusions from novel structures and characterized genomes

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Structure-guided engineering of xylitol dehydrogenase cosubstrate specificity

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

The expression of a Pichia stipitis xylose reductase mutant with higher K(M) for NADPH increases ethanol production from xylose in recombinant Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Intracellular fluxes in a recombinant xylose-utilizing Saccharomyces cerevisiae cultivated anaerobically at different dilution rates and feed concentrations

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Utilization of xylitol dehydrogenase in a combined microbial/enzymatic process for production of xylitol from D-glucose

1 reference

https://api.crossref.org/works/10.1186%2F1475-2859-7-9

21 January 2018

Furfural, 5-hydroxymethyl furfural, and acetoin act as external electron acceptors during anaerobic fermentation of xylose in recombinant Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

26 November 2018

Xylose-metabolizing Saccharomyces cerevisiae strains overexpressing the TKL1 and TAL1 genes encoding the pentose phosphate pathway enzymes transketolase and transaldolase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2315639

26 November 2018

Amino acid substitutions in the yeast Pichia stipitis xylitol dehydrogenase coenzyme-binding domain affect the coenzyme specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18346277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High activity of xylose reductase and xylitol dehydrogenase improves xylose fermentation by recombinant Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18346277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of the role of the conserved lysine-270 in the Pichia stipitis xylose reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18346277

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1475-2859-7-9

1 reference

Europe PubMed Central

14 November 2017

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1475-2859-7-9

1 reference

Europe PubMed Central

14 November 2017

1 reference

Europe PubMed Central

14 November 2017

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