(Q30495248)

English

Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

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Karsten Jürchott

5

object named as

Karsten Jürchott

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

author name string

Till Krech

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Margarethe Thiede

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Ellen Hilgenberg

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Reinhold Schäfer

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

language of work or name

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publication date

14 June 2010

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

10

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

287

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

ASPM and citron kinase co-localize to the midbody ring during cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

A role for NuSAP in linking microtubules to mitotic chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Phospholipase C isoforms are localized at the cleavage furrow during cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Phosphoinositide signaling plays a key role in cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Regulation of the actin cytoskeleton by PIP2 in cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Exploiting the PI3K/AKT pathway for cancer drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

EXPANDER--an integrative program suite for microarray data analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Ablation of PRC1 by small interfering RNA demonstrates that cytokinetic abscission requires a central spindle bundle in mammalian cells, whereas completion of furrowing does not

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

High frequency of mutations of the PIK3CA gene in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Phosphatidylinositol Phosphate Kinases Put PI4,5P 2 in Its Place

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Controlling calcium entry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Signaling by distinct classes of phosphoinositide 3-kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895615

20 June 2018

Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockou

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-287

21 January 2018

Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-287

21 January 2018

AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-287

21 January 2018

Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-287

21 January 2018

Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-287

21 January 2018

Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-287

21 January 2018

Resveratrol inhibits polyphosphoinositide metabolism in activated platelets

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-287

21 January 2018

Dopamine stimulates45Ca2+ uptake through cAMP, PLC/PKC, and MAPKs in renal proximal tubule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20546605

12 December 2020

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Identifiers

10.1186/1471-2407-10-287

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

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