(Q30496451)

10 October 2017

Inactivation of Patched1 in the mouse limb has novel inhibitory effects on the chondrogenic program (English)

1 reference

10 October 2017

5

1 reference

10 October 2017

Vicki Metzis

3

0 references

Carol Wicking

object named as

Carol Wicking

6

0 references

author name string

Stephen J Bruce

1

1 reference

10 October 2017

Natalie C Butterfield

2

1 reference

10 October 2017

Liam Town

4

1 reference

10 October 2017

language of work or name

English

0 references

publication date

24 June 2010

1 reference

Journal of Biological Chemistry

10 October 2017

1 reference

10 October 2017

285

1 reference

10 October 2017

36

1 reference

10 October 2017

27967-27981

1 reference

describes a project that uses

10 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2934663/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complex

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Role of RhoC in digit morphogenesis during limb development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Fibroblast growth factors 2, 4, and 8 exert both negative and positive effects on limb, frontonasal, and mandibular chondrogenesis via MEK-ERK activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Birth and death of cells in limb development: a mapping study.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

The control of chondrogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Hedgehog signaling and congenital malformations

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Genomic screen for genes involved in mammalian craniofacial development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

The transcription factors L-Sox5 and Sox6 are essential for cartilage formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Hedgehog proteins stimulate chondrogenic cell differentiation and cartilage formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

All for one and one for all: condensations and the initiation of skeletal development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Sox9 is required for cartilage formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Altered neural cell fates and medulloblastoma in mouse patched mutants

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

SOX9 directly regulates the type-II collagen gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Retinoic acid receptor alpha function in vertebrate limb skeletogenesis: a modulator of chondrogenesis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

The role of Pax-1 in axial skeleton development.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

All for one and one for all: condensations and the initiation of skeletal development

14 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

Visualization of cartilage formation: insight into cellular properties of skeletal progenitors and chondrodysplasia syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

RhoA/ROCK signaling regulates chondrogenesis in a context-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

Sonic hedgehog protein promotes proliferation and chondrogenic differentiation of bone marrow-derived mesenchymal stem cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

Patched 1 conditional null allele in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

Analysis of N-cadherin function in limb mesenchymal chondrogenesis in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.091785

Dual action of sonic hedgehog on chondrocyte hypertrophy: retrovirus mediated ectopic sonic hedgehog expression in limb bud micromass culture induces novel cartilage nodules that are positive for alkaline phosphatase and type X collagen

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2934663

Wnt/beta-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation

26 November 2018

1 reference

12 December 2020

Nosology and classification of genetic skeletal disorders: 2006 revision

1 reference

12 December 2020

BMPs are required at two steps of limb chondrogenesis: formation of prechondrogenic condensations and their differentiation into chondrocytes

1 reference

12 December 2020

Expression of Cre recombinase in the developing mouse limb bud driven by aPrxl enhancer

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.091785

1 reference

10 October 2017

1 reference

10 October 2017

1 reference