(Q30497778)

English

Constraint-based, homology model of the extracellular domain of the epithelial Na+ channel α subunit reveals a mechanism of channel activation by proteases

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Constraint-based, homology model of the extracellular domain of the epithelial Na+ channel α subunit reveals a mechanism of channel activation by proteases (English)

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

author name string

Ossama B Kashlan

1

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Joshua L Adelman

2

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Sora Okumura

3

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Brandon M Blobner

4

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Zachary Zuzek

5

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Rebecca P Hughey

6

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Thomas R Kleyman

7

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Michael Grabe

8

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

language of work or name

0 references

publication date

25 October 2010

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

286

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

1

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

649-660

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

describes a project that uses

1 reference

Europe PubMed Central

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

based on heuristic

inferred from PubMed Central ID database lookup

Allosteric Inhibition of the Epithelial Na+ Channel through Peptide Binding at Peripheral Finger and Thumb Domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Extracellular allosteric regulatory subdomain within the gamma subunit of the epithelial Na+ channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

On the functional significance of soft modes predicted by coarse-grained models for membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

New role for plasmin in sodium homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Extracellular chloride regulates the epithelial sodium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Structure and function of Na(+)-symporters with inverted repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

ENaC at the cutting edge: regulation of epithelial sodium channels by proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Novel determinants of epithelial sodium channel gating within extracellular thumb domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Extracellular protons regulate human ENaC by modulating Na+ self-inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Plasmin activates epithelial Na+ channels by cleaving the gamma subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

The Jpred 3 secondary structure prediction server

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Insight toward epithelial Na+ channel mechanism revealed by the acid-sensing ion channel 1 structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Comparative protein structure modeling using Modeller

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Prostasin expression is regulated by airway surface liquid volume and is increased in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

A segment of gamma ENaC mediates elastase activation of Na+ transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Clustal W and Clustal X version 2.0

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Epithelial Na+ channel subunit stoichiometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

The PredictProtein server

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

MMTSB Tool Set: enhanced sampling and multiscale modeling methods for applications in structural biology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Epithelial sodium channels are activated by furin-dependent proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Cytoscape: a software environment for integrated models of biomolecular interaction networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Protons at the gate: DEG/ENaC ion channels help us feel and remember

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Protein structure prediction and structural genomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Anisotropy of fluctuation dynamics of proteins with an elastic network model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Cascaded multiple classifiers for secondary structure prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Exploiting the past and the future in protein secondary structure prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Protein secondary structure prediction based on position-specific scoring matrices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Recognition of errors in three-dimensional structures of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

The relation between the divergence of sequence and structure in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Current-voltage curve of sodium channels and concentration dependence of sodium permeability in frog skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013024

20 June 2018

Extracellular histidine residues crucial for Na+ self-inhibition of epithelial Na+ channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.167098

21 January 2018

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.167098

21 January 2018

Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.167098

21 January 2018

Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.167098

21 January 2018

Effects of receptor-mediated endocytosis and tubular protein composition on volume retention in experimental glomerulonephritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.167098

21 January 2018

Metagrowth: a new resource for the building of metabolic hypotheses in microbiology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.167098

21 January 2018

Anisotropic network model: systematic evaluation and a new web interface.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.167098

21 January 2018

Functional role of extracellular loop cysteine residues of the epithelial Na+ channel in Na+ self-inhibition.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.167098

21 January 2018

Epithelial Na+ channels are activated by laminar shear stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.167098

21 January 2018

Use of secondary structural information and C alpha-C alpha distance restraints to model protein structures with MODELLER

1 reference

https://pubmed.ncbi.nlm.nih.gov/20974852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.167098

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q30497778&oldid=1657443148"