(Q30497860)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Presenilin-2 mutation causes early amyloid accumulation and memory impairment in a transgenic mouse model of Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Toshihiko Toda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Genzo Ito

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Masahiro Maeda

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Takahiko Shimizu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

29 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomedicine and Biotechnology

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

617974

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

20 January 2020

copyright license

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Presenilin/gamma-Secretase and Inflammation

1 reference

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Protein aggregation diseases: pathogenicity and therapeutic perspectives

20 June 2018

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Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

20 June 2018

1 reference

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Developing preventive therapies for chronic diseases: lessons learned from Alzheimer's disease

20 June 2018

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Generation of Abeta38 and Abeta42 is independently and differentially affected by familial Alzheimer disease-associated presenilin mutations and gamma-secretase modulation

20 June 2018

1 reference

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Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease

20 June 2018

1 reference

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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

20 June 2018

1 reference

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Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B.

20 June 2018

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Aspects of spatial memory and behavioral disinhibition in Tg2576 transgenic mice as a model of Alzheimer's disease

20 June 2018

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Transgenic mouse models of Alzheimer's disease: phenotype and application

20 June 2018

1 reference

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The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

20 June 2018

1 reference

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Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin

20 June 2018

1 reference

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Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain.

20 June 2018

1 reference

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Mutant genes in familial Alzheimer's disease and transgenic models

20 June 2018

1 reference

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

20 June 2018

1 reference

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The Alzheimer family of diseases: many etiologies, one pathogenesis?

20 June 2018

1 reference

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The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

20 June 2018

1 reference

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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018662

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

20 June 2018

1 reference

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018662

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

20 June 2018

1 reference

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Developments of a water-maze procedure for studying spatial learning in the rat

20 June 2018

1 reference

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

20 June 2018

1 reference

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Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice

21 January 2018

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Neuropathological and clinical phenotype of an Italian Alzheimer family with M239V mutation of presenilin 2 gene.

21 January 2018

1 reference

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Ameliorative effects of yokukansan, a traditional Japanese medicine, on learning and non-cognitive disturbances in the Tg2576 mouse model of Alzheimer's disease

21 January 2018

1 reference

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Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease

21 January 2018

1 reference

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Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography

21 January 2018

1 reference

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PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.

21 January 2018

1 reference

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Amyloid beta protein (A beta) deposition: A beta 42(43) precedes A beta 40 in Down syndrome

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21234330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transgenic mouse models of Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21234330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2011/617974

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21234330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference