(Q30502320)

10 August 2017

Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking (English)

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10 August 2017

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1 reference

1 reference

Pia Steensland

1

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author name string

Jeffrey A Simms

2

1 reference

10 August 2017

Joan Holgate

3

1 reference

10 August 2017

Jemma K Richards

4

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10 August 2017

Selena E Bartlett

5

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10 August 2017

language of work or name

English

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publication date

11 July 2007

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Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

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10 August 2017

104

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10 August 2017

30

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10 August 2017

12518-12523

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Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Alcohol's actions on neuronal nicotinic acetylcholine receptors.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

The status of naltrexone in the treatment of alcohol dependence: specific effects on heavy drinking

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Targeting treatments for alcohol dependence: the pharmacogenetics of naltrexone

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Effect of maintenance therapy with varenicline on smoking cessation: a randomized controlled trial

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Nicotine addiction and comorbidity with alcohol abuse and mental illness

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Posttreatment results of combining naltrexone with cognitive-behavior therapy for the treatment of alcoholism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Nicotinic receptors in the brain: correlating physiology with function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Neuronal nicotinic acetylcholine receptors: a new target site of ethanol

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Ethanol modulation of nicotinic acetylcholine receptor currents in cultured cortical neurons.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Identification of four classes of brain nicotinic receptors using beta2 mutant mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Accumbal dopamine overflow after ethanol: localization of the antagonizing effect of mecamylamine.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Naltrexone blocks the post-shock increase of ethanol consumption

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Naltrexone in the treatment of alcohol dependence

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Central opioid receptor subtype antagonists differentially alter sucrose and deprivation-induced water intake in rats

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Alteration of ethanol self-administration by naltrexone.

14 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Effect of acamprosate and naltrexone, alone or in combination, on ethanol consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Effects of naltrexone administered repeatedly across 30 or 60 days on ethanol consumption using a limited access procedure in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

A comparison of the effects of 6-beta naltrexol and naltrexone on the consumption of ethanol or sucrose using a limited-access procedure in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Voluntary ethanol intake in the rat and the associated accumbal dopamine overflow are blocked by ventral tegmental mecamylamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Involvement of nicotinic receptors in alcohol self-administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Mecamylamine modifies the pharmacokinetics and reinforcing effects of alcohol

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Mecamylamine attenuates the subjective stimulant-like effects of alcohol in social drinkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Mecamylamine and ethanol preference in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Voluntary ethanol intake increases extracellular acetylcholine levels in the ventral tegmental area in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

In alcohol-treated rats, naloxone decreases extracellular dopamine and increases acetylcholine in the nucleus accumbens: evidence of opioid withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Effects of ethanol on excitatory and inhibitory synaptic transmission in rat cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Potential regulation of nicotine and ethanol actions by alpha4-containing nicotinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Interaction of the Nicotinic Cholinergic System with Ethanol Withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Alpha 4 beta 2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Role of different nicotinic acetylcholine receptors in mediating behavioral and neurochemical effects of ethanol in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Ethanol elevates accumbal dopamine levels via indirect activation of ventral tegmental nicotinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

The effect of chronic ethanol administration of high affinity 3H-nicotinic binding in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Ethanol modulates nicotine-induced upregulation of nAChRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

A double-blind study evaluating the long-term safety of varenicline for smoking cessation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Reinstatement of ethanol-seeking behavior by drug cues following single versus multiple ethanol intoxication in the rat: effects of naltrexone

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Hypericum perforatum CO2 Extract and Opioid Receptor Antagonists Act Synergistically to Reduce Ethanol Intake in Alcohol‐Preferring Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705368104

Effects of combined systemic alcohol and central nicotine administration into ventral tegmental area on dopamine release in the nucleus accumbens

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Effects of ethanol on recombinant human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Heavy consumption of cigarettes, alcohol and coffee in male twins.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1914040

Voluntary ethanol intake in rats following exposure to ethanol on various schedules

26 November 2018

1 reference

12 December 2020

Naloxone attenuates voluntary ethanol intake in rats selectively bred for high ethanol preference

1 reference

12 December 2020

Naltrexone and coping skills therapy for alcohol dependence. A controlled study

1 reference

12 December 2020

Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment

1 reference

12 December 2020

Attenuation of alcohol consumption by a novel nontoxic ibogaine analogue (18-methoxycoronaridine) in alcohol-preferring rats

1 reference

12 December 2020

Naltrexone as an adjunctive treatment for older patients with alcohol dependence

1 reference

12 December 2020

Role of the subunit composition of central nicotinic acetylcholine receptors for the stimulatory and dopamine-enhancing effects of ethanol

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0705368104

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10 August 2017

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10 August 2017

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