(Q30505415)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

AMF-26, a novel inhibitor of the Golgi system, targeting ADP-ribosylation factor 1 (Arf1) with potential for cancer therapy (English)

1 reference

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18 January 2020

3

1 reference

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18 January 2020

author name string

Yoshimi Ohashi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Hiroshi Iijima

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Kanami Yamazaki

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Shigeo Sato

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Mutsumi Okamura

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Kenji Sugimoto

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Shingo Dan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Shuichi Hirono

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Takao Yamori

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

9 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

18 January 2020

published in

1 reference

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18 January 2020

volume

287

1 reference

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18 January 2020

issue

6

1 reference

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18 January 2020

page(s)

3885-3897

1 reference

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describes a project that uses

18 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3281721/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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14 July 2018

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14 July 2018

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Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR39.

14 July 2018

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Golgicide A reveals essential roles for GBF1 in Golgi assembly and function

14 July 2018

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A novel small molecule regulator of guanine nucleotide exchange activity of the ADP-ribosylation factor and golgi membrane trafficking.

14 July 2018

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Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy.

14 July 2018

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14 July 2018

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Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes

14 July 2018

1 reference

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Unfolded protein response and cell death after depletion of brefeldin A-inhibited guanine nucleotide-exchange protein GBF1

14 July 2018

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Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

14 July 2018

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Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors

14 July 2018

1 reference

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Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes

14 July 2018

1 reference

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Rhythmic cycle of clathrin-coated pit formation at the trans-golgi network in human MDA-MB-435 cells

14 July 2018

1 reference

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The NCI60 human tumour cell line anticancer drug screen

14 July 2018

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Synthesis and anticancer activity of brefeldin A ester derivatives

14 July 2018

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The ER-Golgi intermediate compartment (ERGIC): in search of its identity and function

14 July 2018

1 reference

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ARF proteins: roles in membrane traffic and beyond

14 July 2018

1 reference

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Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor

14 July 2018

1 reference

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Dynamics of GBF1, a Brefeldin A-sensitive Arf1 exchange factor at the Golgi

14 July 2018

1 reference

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Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells

14 July 2018

1 reference

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Development and testing of a general amber force field

14 July 2018

1 reference

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The structure and function of GGAs, the traffic controllers at the TGN sorting crossroads

14 July 2018

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Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor

14 July 2018

1 reference

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Panel of human cancer cell lines provides valuable database for drug discovery and bioinformatics

14 July 2018

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Exo1: a new chemical inhibitor of the exocytic pathway

14 July 2018

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Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network

14 July 2018

1 reference

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Dissection of COPI and Arf1 dynamics in vivo and role in Golgi membrane transport

14 July 2018

1 reference

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GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors

14 July 2018

1 reference

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The GGAs promote ARF-dependent recruitment of clathrin to the TGN

14 July 2018

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Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel

14 July 2018

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FJ5002: a potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis.

14 July 2018

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Structure of the guanine nucleotide exchange factor Sec7 domain of human arno and analysis of the interaction with ARF GTPase

14 July 2018

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Antiproliferative effect in vitro and antitumor activity in vivo of brefeldin A.

14 July 2018

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Kinetics of monensin-induced swelling of Golgi apparatus cisternae of H-2 hepatoma cells.

14 July 2018

1 reference

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Subpopulations of microtubules with differential sensitivity to nocodazole: role in the structural organization of the Golgi complex and the lysosomal system.

14 July 2018

1 reference

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Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

14 July 2018

1 reference

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Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER

14 July 2018

1 reference

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New colorimetric cytotoxicity assay for anticancer-drug screening

14 July 2018

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Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

14 July 2018

1 reference

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Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281721

Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281721

Brefeldin A binds to glutathione S-transferase and is secreted as glutathione and cysteine conjugates by Chinese hamster ovary cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281721

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

14 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.316125

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.316125

Comparison of simple potential functions for simulating liquid water

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.316125

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

21 January 2018

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Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111.316125

Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status: in silico and biological evaluations

21 January 2018

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CAMDAS: an automated conformational analysis system using molecular dynamics. Conformational Analyzer with Molecular Dynamics And Sampling

21 January 2018

1 reference

12 December 2020

Estimation of active conformations of drugs by a new molecular superposing procedure

1 reference

12 December 2020

Dual specificity of the interfacial inhibitor brefeldin a for arf proteins and sec7 domains

1 reference

12 December 2020

Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2

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12 December 2020

An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines

1 reference

12 December 2020

Role of microtubules in the organization of the Golgi complex

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.316125

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22158626%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

22158626

1 reference