(Q30515538)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Mrudang M. Shah

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

2

Michael J Kane

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Mariana Angoa-Pérez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Catherine E Sykes

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Dina M Francescutti

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

David R Rosenberg

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

David M Thomas

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Donald M Kuhn

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

13 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neurochemistry

26 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

121

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

974-984

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences.

26 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Grand challenges in global mental health

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Animal models of obsessive-compulsive disorder: exploring pharmacology and neural substrates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

A transient placental source of serotonin for the fetal forebrain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Animal models of anxiety and anxiolytic drug action.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: a perspective.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

A population-specific HTR2B stop codon predisposes to severe impulsivity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Genetic models of serotonin (5-HT) depletion: what do they tell us about the developmental role of 5-HT?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

The role of endogenous serotonin in methamphetamine-induced neurotoxicity to dopamine nerve endings of the striatum

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Serotonin: a regulator of neuronal morphology and circuitry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Tryptophan-hydroxylase 2 haplotype association with borderline personality disorder and aggression in a sample of patients with personality disorders and healthy controls

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Mouse plasmacytoma-expressed transcript 1 knock out induced 5-HT disruption results in a lack of cognitive deficits and an anxiety phenotype complicated by hypoactivity and defensiveness.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Growth retardation and altered autonomic control in mice lacking brain serotonin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Behavioral disinhibition and the development of early-onset addiction: common and specific influences

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Neural mechanisms of aggression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Neural systems implicated in delayed and probabilistic reinforcement

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Compulsive aspects of impulse-control disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

From genes to aggressive behavior: the role of serotonergic system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Behavioral models of impulsivity in relation to ADHD: translation between clinical and preclinical studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Hoxb8 is required for normal grooming behavior in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

20 June 2018

Varieties of impulsivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Defective limbic system in mice lacking the tailless gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Serotonin as a developmental signal

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Intruder-evoked aggression in isolated and nonisolated mice: Effects of psychomotor stimulants and l-Dopa

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

Absence of 5-HT(1B) receptors is associated with impaired impulse control in male 5-HT(1B) knockout mice

20 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

Insights into the neurobiology of impulsive behavior from serotonin receptor knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

Compulsive behavior in the 5-HT2C receptor knockout mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

A genetically defined morphologically and functionally unique subset of 5-HT neurons in the mouse raphe nuclei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

Activation of dorsal raphe serotonin neurons underlies waiting for delayed rewards.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

Visuo-spatial learning and memory deficits on the Barnes maze in the 16-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

Serotonin transporter, 5-HT1A receptor, and behavior in DBA/2J mice in comparison with four inbred mouse strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

Enhanced aggressive behavior in mice lacking 5-HT1B receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2012.07739.X

Animal models of obsessive-compulsive disorder

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371128

10.1111/J.1471-4159.2012.07739.X

26 November 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22443164%20AND%20SRC:MED&resulttype=core&format=json