(Q30515819)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

author name string

Alexander Babich

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Shuixing Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Roddy S O'Connor

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Michael C Milone

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Bruce D Freedman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

language of work or name

English

0 references

publication date

4 June 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

number of pages

13

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

volume

197

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

page(s)

775-787

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

3 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3373411/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells

20 June 2018

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20 June 2018

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Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cells

20 June 2018

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20 June 2018

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20 June 2018

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Altered actin centripetal retrograde flow in physically restricted immunological synapses

20 June 2018

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Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse.

20 June 2018

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Myosin II contributes to cell-scale actin network treadmilling through network disassembly

20 June 2018

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Hematopoietic lineage cell-specific protein 1 is recruited to the immunological synapse by IL-2-inducible T cell kinase and regulates phospholipase Cgamma1 Microcluster dynamics during T cell spreading

20 June 2018

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Neuronal IP3 3-kinase is an F-actin-bundling protein: role in dendritic targeting and regulation of spine morphology

20 June 2018

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The alphabeta T cell receptor is an anisotropic mechanosensor.

20 June 2018

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Calcium signaling in the development and function of T-lineage cells

20 June 2018

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The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells

20 June 2018

1 reference

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T cell antigen receptor signaling and immunological synapse stability require myosin IIA

20 June 2018

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20 June 2018

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The actin cytoskeleton in T cell activation

20 June 2018

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Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

20 June 2018

1 reference

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Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility

20 June 2018

1 reference

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Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse

20 June 2018

1 reference

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20 June 2018

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Persistence of cooperatively stabilized signaling clusters drives T-cell activation

20 June 2018

1 reference

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20 June 2018

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T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

20 June 2018

1 reference

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The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation

20 June 2018

1 reference

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Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

20 June 2018

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20 June 2018

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Two distinct actin networks drive the protrusion of migrating cells

20 June 2018

1 reference

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Binding specificity of multiprotein signaling complexes is determined by both cooperative interactions and affinity preferences

20 June 2018

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A single class II myosin modulates T cell motility and stopping, but not synapse formation

20 June 2018

1 reference

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Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor

20 June 2018

1 reference

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T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

20 June 2018

1 reference

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T cell receptor signaling precedes immunological synapse formation

20 June 2018

1 reference

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Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells

20 June 2018

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Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

20 June 2018

1 reference

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The immunological synapse: a molecular machine controlling T cell activation

20 June 2018

1 reference

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Intracellular calcium dependence of gene expression in single T lymphocytes

20 June 2018

1 reference

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PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.

20 June 2018

1 reference

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Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.

20 June 2018

1 reference

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HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201201018

Cutting Edge: mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling.

21 January 2018

1 reference

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Altered TCR signaling from geometrically repatterned immunological synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201201018

Disruption of the cortical actin cytoskeleton does not affect store operated Ca2+ channels in human T-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201201018

B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201201018

Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201201018

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201201018

Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201201018

Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373411

T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76

26 November 2018

1 reference

12 December 2020

The selective role of myosin VI in lymphoid leukemia cell migration

1 reference

12 December 2020

The space and time frames of T cell activation at the immunological synapse

1 reference

12 December 2020

High-resolution multicolor imaging of dynamic signaling complexes in T cells stimulated by planar substrates

1 reference

12 December 2020

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.201201018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

22665519

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22665519%20AND%20SRC:MED&resulttype=core&format=json