(Q30519991)

12 August 2017

Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila (English)

1 reference

Spiros Artavanis-Tsakonas

12 August 2017

0 references

5

object named as

Spyros Artavanis-Tsakonas

1 reference

12 August 2017

S K Pallavi

1

1 reference

12 August 2017

Diana M Ho

2

1 reference

12 August 2017

Chindo Hicks

3

1 reference

12 August 2017

Lucio Miele

4

1 reference

12 August 2017

language of work or name

English

0 references

publication date

11 May 2012

1 reference

12 August 2017

1 reference

12 August 2017

31

1 reference

12 August 2017

13

1 reference

12 August 2017

2895-2907

1 reference

Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signalling in solid tumours: a little bit of everything but not all the time

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

RANKL inhibition: a promising novel strategy for breast cancer treatment.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

MMP-1-PAR1 axis mediates LPA-induced epithelial ovarian cancer (EOC) invasion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch: The Past, the Present, and the Future

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Targeting Notch to target cancer stem cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Identification of novel Notch target genes in T cell leukaemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The canonical Notch signaling pathway: unfolding the activation mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Disruption of Vps4 and JNK function in Drosophila causes tumour growth

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The Notch signaling pathway: transcriptional regulation at Notch target genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

MEF2: a central regulator of diverse developmental programs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Character Changes Caused by Mutation of an Entire Region of a Chromosome in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signalling: a simple pathway becomes complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

A Temporal Map of Transcription Factor Activity: Mef2 Directly Regulates Target Genes at All Stages of Muscle Development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Exploring a new twist on tumor metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Invasive cell behavior during Drosophila imaginal disc eversion is mediated by the JNK signaling cascade

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The control of cell motility and epithelial morphogenesis by Jun kinases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

A Genetic Screen in Drosophila for Metastatic Behavior

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signaling and inherited disease syndromes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Inflammation and cancer: back to Virchow?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signaling: cell fate control and signal integration in development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Boundary formation in Drosophila wing: Notch activity attenuated by the POU protein Nubbin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

wingless inhibits morphogenetic furrow movement in the Drosophila eye disc.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The relationship of decapentaplegic and engrailed expression in Drosophila imaginal disks: do these genes mark the anterior-posterior compartment boundary?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signaling in leukemia

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Notch signaling directly controls cell proliferation in the Drosophila wing disc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Drosophila MEF2, a transcription factor that is essential for myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Nodal points and complexity of Notch-Ras signal integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by Dark and DRONC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Requirement of MADS domain transcription factor D-MEF2 for muscle formation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Mutations within the conserved MADS box of the D-MEF2 muscle differentiation factor result in a loss of DNA binding ability and lethality in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

The role of Notch in tumorigenesis: oncogene or tumour suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

A series of mutations in the D-MEF2 transcription factor reveal multiple functions in larval and adult myogenesis in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Cell proliferation control by Notch signaling in Drosophila development.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Twist and Notch negatively regulate adult muscle differentiation in Drosophila.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The wingless signalling pathway and the patterning of the wing margin in Drosophila.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing

26 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Notch signals control the fate of immature progenitor cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

TNF-alpha enhances estrogen-induced cell proliferation of estrogen-dependent breast tumor cells through a complex containing nuclear factor-kappa B

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22580825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22580825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2012.129

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22580825

1 reference