(Q30543591)

18 August 2017

Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2. (English)

1 reference

Epidermal growth factor receptor pathway substrate 8

18 August 2017

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

4

0 references

Walter Marcotti

20

0 references

Marlies Knipper

16

0 references

Sergio Masetto

14

0 references

Pier Paolo Di Fiore

13

0 references

Arianna Tocchetti

5

0 references

Uri Manor

object named as

Uri Manor

3

0 references

Nina Offenhauser

object named as

Nina Offenhauser

6

0 references

Matthew Holley

object named as

Matthew C Holley

17

0 references

author name string

David N Furness

1

1 reference

18 August 2017

Stuart L Johnson

2

1 reference

18 August 2017

Jennifer Olt

7

1 reference

18 August 2017

Richard J Goodyear

8

1 reference

18 August 2017

Sarath Vijayakumar

9

1 reference

18 August 2017

Yuhai Dai

10

1 reference

18 August 2017

Carole M Hackney

11

1 reference

18 August 2017

Christoph Franz

12

1 reference

18 August 2017

Sherri M Jones

15

1 reference

18 August 2017

Guy P Richardson

18

1 reference

18 August 2017

Bechara Kachar

19

1 reference

18 August 2017

language of work or name

English

0 references

publication date

5 August 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

1 reference

18 August 2017

110

1 reference

18 August 2017

34

1 reference

18 August 2017

13898-13903

1 reference

GRM7 variants associated with age-related hearing loss based on auditory perception

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Hair bundle defects and loss of function in the vestibular end organs of mice lacking the receptor-like inositol lipid phosphatase PTPRQ

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Ezrin regulates microvillus morphogenesis by promoting distinct activities of Eps8 proteins.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Actin in hair cells and hearing loss

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Prestin-driven cochlear amplification is not limited by the outer hair cell membrane time constant

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Roles of the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic jerker mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Gravity receptor aging in the CBA/CaJ strain: a comparison to auditory aging

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Review series: The cell biology of hearing

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Twinfilin 2 regulates actin filament lengths in cochlear stereocilia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Gamma-actin is required for cytoskeletal maintenance but not development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Linking genes underlying deafness to hair-bundle development and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Fast adaptation and Ca2+ sensitivity of the mechanotransducer require myosin-XVa in inner but not outer cochlear hair cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Dynamic length regulation of sensory stereocilia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

KCNQ4: a gene for age-related hearing impairment?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

The sensory and motor roles of auditory hair cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Eps8 controls actin-based motility by capping the barbed ends of actin filaments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Transient expression of the t-isoform of plastins/fimbrin in the stereocilia of developing auditory hair cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

The deaf jerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Parallel actin bundles and their multiple actin-bundling proteins.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

EPS8 and E3B1 transduce signals from Ras to Rac

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Postnatal development of the hamster cochlea. II. Growth and differentiation of stereocilia bundles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Actin filaments, stereocilia, and hair cells of the bird cochlea. V. How the staircase pattern of stereociliary lengths is generated

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Actin filaments, stereocilia, and hair cells: how cells count and measure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752214

Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1304644110

Balanced levels of Espin are critical for stereociliary growth and length maintenance.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1304644110

Actin-binding proteins sensitively mediate F-actin bundle stiffness

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23918390

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Morphology of inner hair cell stereocilia in C57BL/6J mice as studied by scanning electron microscopy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23918390

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1304644110

1 reference

18 August 2017

0 references

1 reference

18 August 2017

1 reference