(Q30574010)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Damnacanthal, an effective inhibitor of LIM-kinase, inhibits cell migration and invasion (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

Kazumasa Ohashi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Kaori Sampei

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Mami Nakagawa

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Naoto Uchiumi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Tatsuya Amanuma

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Setsuya Aiba

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Kensaku Mizuno

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

publication date

29 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

Molecular Biology of the Cell

6 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

page(s)

828-840

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

6 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3952852/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Functions of cofilin in cell locomotion and invasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

LIM kinases are attractive targets with many macromolecular partners and only a few small molecule regulators

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

LIM kinase has a dual role in regulating lamellipodium extension by decelerating the rate of actin retrograde flow and the rate of actin polymerization.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

LIM-kinase is critical for the mesenchymal-to-amoeboid cell morphological transition in 3D matrices.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Visualization of molecular interactions using bimolecular fluorescence complementation analysis: characteristics of protein fragment complementation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Small molecule inhibitors of Lck: the search for specificity within a kinase family

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

The cofilin pathway in breast cancer invasion and metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Mechanism of depolymerization and severing of actin filaments and its significance in cytoskeletal dynamics.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

LIM kinases: function, regulation and association with human disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

SH2 and PTB domains in tyrosine kinase signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

A role for LIM kinase in cancer invasion.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Cellular motility driven by assembly and disassembly of actin filaments

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

ADF/cofilin and actin dynamics in disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

The protein kinase complement of the human genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Protein kinases--the major drug targets of the twenty-first century?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Lck is required for stromal cell-derived factor 1 alpha (CXCL12)-induced lymphoid cell chemotaxis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Stromal cell-derived factor 1alpha activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Langerhans cell migration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Cytokines and chemokines in the initiation and regulation of epidermal Langerhans cell mobilization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Actin depolymerizing factor and cofilin phosphorylation dynamics: response to signals that regulate neurite extension

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Inhibition of T lymphocyte activation by a novel p56lck tyrosine kinase inhibitor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Ia+ murine epidermal Langerhans cells are deficient in surface expression of the class I major histocompatibility complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Phenotypic and functional characteristics of in vivo-activated Langerhans cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

Emodin, a protein tyrosine kinase inhibitor from Polygonum cuspidatum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952852

A-420983: a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection

28 July 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck -- a selectivity insight

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

Recent findings confirm LIM domain kinases as emerging target candidates for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

CaMKIIβ-mediated LIM-kinase activation plays a crucial role in BDNF-induced neuritogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E13-09-0540

Visualization of cofilin-actin and Ras-Raf interactions by bimolecular fluorescence complementation assays using a new pair of split Venus fragments

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24478456

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cytochalasin D acts as an inhibitor of the actin-cofilin interaction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24478456

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E13-09-0540

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24478456%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

24478456

1 reference