(Q30585642)

1 November 2017

SARConnect: A Tool to Interrogate the Connectivity Between Proteins, Chemical Structures and Activity Data (English)

1 reference

1 November 2017

4

1 reference

PubMed publication ID

25 June 2017

8

0 references

author name string

Mats Eriksson

1

1 reference

1 November 2017

Ingemar Nilsson

2

1 reference

1 November 2017

Thierry Kogej

3

1 reference

1 November 2017

Martin Johansson

5

1 reference

1 November 2017

Christian Tyrchan

6

1 reference

1 November 2017

Sorel Muresan

7

1 reference

1 November 2017

Marcus Bjäreland

9

1 reference

1 November 2017

7 August 2012

1 reference

1 November 2017

Molecular Informatics

1 reference

1 November 2017

31

1 reference

1 November 2017

8

1 reference

1 November 2017

555-568

1 reference

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

1 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

NucleaRDB: information system for nuclear receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Making every SAR point count: the development of Chemistry Connect for the large-scale integration of structure and bioactivity data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Empowering industrial research with shared biomedical vocabularies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

ChEMBL: a large-scale bioactivity database for drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Integrating GPCR-specific information with full text articles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Analysis of in vitro bioactivity data extracted from drug discovery literature and patents: Ranking 1654 human protein targets by assayed compounds and molecular scaffolds

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Present perspectives on the automated classification of the G-protein coupled receptors (GPCRs) at the protein sequence level

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Novel oral factor Xa and thrombin inhibitors in the management of thromboembolism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

IUPHAR-DB: new receptors and tools for easy searching and visualization of pharmacological data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

The chemical basis of pharmacology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

GPCRDB: information system for G protein-coupled receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

PubChem as a public resource for drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

The Protein Ontology: a structured representation of protein forms and complexes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

GPCRRD: G protein-coupled receptor spatial restraint database for 3D structure modeling and function annotation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Anticipating drug side effects by comparative pharmacology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

SARANEA: a freely available program to mine structure-activity and structure-selectivity relationship information in compound data sets

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Enhanced SAR maps: expanding the data rendering capabilities of a popular medicinal chemistry tool.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Interactive exploration of chemical space with Scaffold Hunter

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC stu

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

The Transporter Classification Database: recent advances

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Network pharmacology: the next paradigm in drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Physiochemical drug properties associated with in vivo toxicological outcomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

The annotation of both human and mouse kinomes in UniProtKB/Swiss-Prot: one small step in manual annotation, one giant leap for full comprehension of genomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Structural diversity of G protein-coupled receptors and significance for drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

GLIDA: GPCR--ligand database for chemical genomics drug discovery--database and tools update

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Short-term antiviral activity of TMC278--a novel NNRTI--in treatment-naive HIV-1-infected subjects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

The olfactory receptor universe--from whole genome analysis to structure and evolution.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

A new oral anticoagulant: the 50-year challenge

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

An ontology for pharmaceutical ligands and its application for in silico screening and library design

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

The human proteomics initiative (HPI).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

The properties of known drugs. 1. Molecular frameworks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Fingerprinting G-protein-coupled receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

Collaborative Computational Technologies for Biomedical Research

20 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201200030

Pharmacological modulation of cell death in atherosclerosis: a promising approach towards plaque stabilization?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201200030

Multifingerprint based similarity searches for targeted class compound selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201200030

Lingos, finite state machines, and fast similarity searching.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201200030

Phenolic P2/P3 core motif as thrombin inhibitors--design, synthesis, and X-ray co-crystal structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201200030

The influence of drug-like concepts on decision-making in medicinal chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201200030

Defining optimum lipophilicity and molecular weight ranges for drug candidates-Molecular weight dependent lower logD limits based on permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201200030

Using the Golden Triangle to optimize clearance and oral absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201200030

Physicochemical property profiles of marketed drugs, clinical candidates and bioactive compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201200030

The Impact of Genomics on Drug Discovery

21 January 2018

2 references

https://api.crossref.org/works/10.1002%2FMINF.201200030

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535785

SAR maps: a new SAR visualization technique for medicinal chemists

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23308082

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Properties of known drugs. 2. Side chains

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23308082

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Investigation of the Relationship between Topology and Selectivity for Druglike Molecules

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23308082

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/MINF.201200030

1 reference

1 November 2017

1 reference

1 November 2017

PubMed publication ID

23308082

1 reference