(Q30651035)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11165171%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Antibody libraries in drug and target discovery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11165171%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11165171%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

C Rader

series ordinal

1

1 reference

25 June 2017

publication date

1 January 2001

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11165171%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11165171%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11165171%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11165171%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

36-43

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11165171%20AND%20SRC:MED&resulttype=core&format=json

Biopharmaceutical benchmarks

3 November 2019

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7 January 2021

Continuous cultures of fused cells secreting antibody of predefined specificity

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7 January 2021

Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda

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7 January 2021

Phage display of combinatorial antibody libraries.

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7 January 2021

Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface

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7 January 2021

Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces

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7 January 2021

Making antibody fragments using phage display libraries

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7 January 2021

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site

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7 January 2021

A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals

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7 January 2021

By-passing immunization. Human antibodies from V-gene libraries displayed on phage

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7 January 2021

Biosynthetic polypeptide libraries

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7 January 2021

In vitro display technologies - new tools for drug discovery

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7 January 2021

Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries.

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7 January 2021

Yeast surface display for screening combinatorial polypeptide libraries

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7 January 2021

Antibody affinity maturation using bacterial surface display.

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7 January 2021

Targeted gene delivery to mammalian cells by filamentous bacteriophage

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7 January 2021

Signaling antibodies in cancer therapy

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7 January 2021

Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

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7 January 2021

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library

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7 January 2021

A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies

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7 January 2021

Exploiting recombination in single bacteria to make large phage antibody libraries

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7 January 2021

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides

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7 January 2021

Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries

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7 January 2021

Synthetic human antibodies

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7 January 2021

Designing and optimizing library selection strategies for generating high-affinity antibodies

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7 January 2021

Implications of the diversity of the immunoglobulin gene superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

In vitro evolution of a T cell receptor with high affinity for peptide/MHC.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Directed evolution of a stable scaffold for T-cell receptor engineering.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

The fibronectin type III domain as a scaffold for novel binding proteins

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7 January 2021

Small antibody-like proteins with prescribed ligand specificities derived from the lipocalin fold.

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7 January 2021

Directed evolution of new catalytic activity using the alpha/beta-barrel scaffold

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7 January 2021

Antibody humanization: a case of the 'Emperor's new clothes'?

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7 January 2021

CDR substitutions of a humanized monoclonal antibody (CC49): contributions of individual CDRs to antigen binding and immunogenicity

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7 January 2021

Replacing the complementarity-determining regions in a human antibody with those from a mouse

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7 January 2021

Reshaping human antibodies for therapy

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7 January 2021

Conformational correction mechanisms aiding antigen recognition by a humanized antibody

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7 January 2021

Antibody framework residues affecting the conformation of the hypervariable loops

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7 January 2021

Structural insights into the evolution of an antibody combining site

1 reference

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7 January 2021

A combinatorial library strategy for the rapid humanization of anticarcinoma BR96 Fab.

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7 January 2021

Antibody humanization using monovalent phage display

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7 January 2021

The rabbit antibody repertoire as a novel source for the generation of therapeutic human antibodies.

1 reference

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7 January 2021

Guiding the Selection of Human Antibodies from Phage Display Repertoires to a Single Epitope of an Antigen

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7 January 2021

A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries.

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7 January 2021

Reconstructing Aldolase Antibodies to Alter Their Substrate Specificity and Turnover

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7 January 2021

Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent

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7 January 2021

Generation and characterization of a recombinant human CCR5-specific antibody. A phage display approach for rabbit antibody humanization.

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7 January 2021

Recombinant antibody constructs in cancer therapy

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7 January 2021

Generating improved single-chain Fv molecules for tumor targeting

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7 January 2021

Selection and evolution of high-affinity human anti-viral antibodies

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7 January 2021

Clonal selection and learning in the antibody system

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7 January 2021

Rapid evolution of a protein in vitro by DNA shuffling

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7 January 2021

Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity

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7 January 2021

In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity

1 reference

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7 January 2021

CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range

1 reference

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7 January 2021

Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Antibody arrays for high-throughput screening of antibody-antigen interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Multiple event activation of a generic prodrug trigger by antibody catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Catalytic antibodies as magic bullets

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Evolving catalytic antibodies in a phage-displayed combinatorial library

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Human neoplasms elicit multiple specific immune responses in the autologous host

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Genes expressed in human tumor endothelium

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7 January 2021

Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library

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7 January 2021

Organ targeting in vivo using phage display peptide libraries

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Membrane dipeptidase is the receptor for a lung-targeting peptide identified by in vivo phage display

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

In vivo selection of sFv from phage display libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Homodimerization of tumor-reactive monoclonal antibodies markedly increases their ability to induce growth arrest or apoptosis of tumor cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901595-6

7 January 2021

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope

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7 January 2021

10.1016/S1359-6446(00)01595-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11165171%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference