(Q30659891)

26 June 2017

title

Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases (English)

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26 June 2017

P Wipf

1

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26 June 2017

D C Aslan

series ordinal

2

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26 June 2017

E C Southwick

series ordinal

3

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26 June 2017

J S Lazo

series ordinal

4

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26 June 2017

language of work or name

English

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publication date

1 February 2001

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26 June 2017

number of pages

5

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Bioorganic & Medicinal Chemistry Letters

inferred from page(s)

published in

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26 June 2017

volume

11

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26 June 2017

issue

3

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26 June 2017

page(s)

313-317

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Rapid destruction of human Cdc25A in response to DNA damage

26 June 2017

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7 January 2021

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Protein tyrosine phosphatases: counting the trees in the forest

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Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction

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Combinatorial synthesis and biological evaluation of library of small-molecule Ser/Thr-protein phosphatase inhibitors

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7 January 2021

A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side chain variation

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7 January 2021

Dual G1 and G2/M phase inhibition by SC-alpha alpha delta 9, a combinatorially derived Cdc25 phosphatase inhibitor

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7 January 2021

Identification of new Cdc25 dual specificity phosphatase inhibitors in a targeted small molecule array

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7 January 2021

Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors

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New Cdc25B tyrosine phosphatase inhibitors, nocardiones A and B, produced by Nocardia sp. TP-A0248: taxonomy, fermentation, isolation, structural elucidation and biological properties.

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Synthesis and characterization of a novel class of protein tyrosine phosphatase inhibitors

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7 January 2021

Steroidal derived acids as inhibitors of human Cdc25A protein phosphatase

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7 January 2021

Inhibition of protein phosphatases by Michael adducts of ascorbic acid analogues with alpha,beta-unsaturated carbonyl compounds

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7 January 2021

New azolidinediones as inhibitors of protein tyrosine phosphatase 1B with antihyperglycemic properties

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The solid phase synthesis of tetrahydroisoquinolines having cdc25B inhibitory activity

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7 January 2021

Structure-based discovery of small molecule inhibitors targeted to protein tyrosine phosphatase 1B

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

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7 January 2021

Extracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathway

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7 January 2021

CDC25 phosphatases as potential human oncogenes

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7 January 2021

A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2

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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

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Conjugated enynes as nonaromatic catechol bioisosteres: synthesis, binding experiments, and computational studies of novel dopamine receptor agonists recognizing preferentially the D(3) subtype

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New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl) imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]pip erid -4-yl]amino]propionate (SR 121787) as

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7 January 2021

Novel inhibitors of DNA gyrase: 3D structure based biased needle screening, hit validation by biophysical methods, and 3D guided optimization. A promising alternative to random screening

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7 January 2021

Synthesis and structure-activity relationship of (lactamylvinyl)cephalosporins exhibiting activity against staphylococci, pneumococci, and enterococci

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7 January 2021

Synthesis and biochemical evaluation of N-(4-phenylthiazol-2-yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3-hydroxylase.

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7 January 2021

Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A

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7 January 2021

Synthesis of Sulfonamido-Pseudopeptides: New Chiral Unnatural Oligomers

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7 January 2021

Solid-Phase Synthesis of Vinylogous Sulfonyl Peptides

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7 January 2021

Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle

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7 January 2021

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Identifiers

DOI

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26 June 2017

1 reference