(Q30665304)

12 August 2017

Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's disease (English)

1 reference

12 August 2017

1 reference

Sabine Gretenkord

5

0 references

Vincenzo De Paola

object named as

Vincenzo De Paola

4

0 references

Dominic J Withers

object named as

Dominic Withers

6

0 references

author name string

Ilse S Pienaar

1

1 reference

12 August 2017

Sarah E Gartside

2

1 reference

12 August 2017

Puneet Sharma

3

1 reference

12 August 2017

Joanna L Elson

7

1 reference

12 August 2017

David T Dexter

8

1 reference

12 August 2017

23 September 2015

1 reference

Molecular Neurodegeneration

12 August 2017

1 reference

12 August 2017

10

1 reference

12 August 2017

47

1 reference

Creative Commons Attribution 4.0 International

12 August 2017

start time

23 September 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4580350/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Pedunculopontine cell loss and protein aggregation direct microglia activation in parkinsonian rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

PPNa-DBS for gait and balance disorders in Parkinson's disease: a double-blind, randomised study

20 June 2018

1 reference

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Role of glutamatergic projections from ventral tegmental area to lateral habenula in aversive conditioning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Pharmacogenetic and optical dissection for mechanistic understanding of Parkinson's disease: potential utilities revealed through behavioural assessment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Deficits in motor performance after pedunculopontine lesions in rats--impairment depends on demands of task

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Sex differences in Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Lesions of cholinergic pedunculopontine tegmental nucleus neurons fail to affect cocaine or heroin self-administration or conditioned place preference in rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Whole-brain circuit dissection in free-moving animals reveals cell-specific mesocorticolimbic networks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Mitochondrial abnormality associates with type-specific neuronal loss and cell morphology changes in the pedunculopontine nucleus in Parkinson disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Direct-pathway striatal neurons regulate the retention of decision-making strategies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Cholinergic dysfunction contributes to gait disturbance in early Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Closing the gap between clinic and cage: sensori-motor and cognitive behavioural testing regimens in neurotoxin-induced animal models of Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

The interplay of cholinergic function, attention, and falls in Parkinson's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Topographical Organization of the Pedunculopontine Nucleus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

History of falls in Parkinson disease is associated with reduced cholinergic activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Non-motor functions in parkinsonian patients implanted in the pedunculopontine nucleus: focus on sleep and cognitive domains.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Pedunculopontine and laterodorsal tegmental nuclei contain distinct populations of cholinergic, glutamatergic and GABAergic neurons in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

The firing activity of presumed cholinergic and non-cholinergic neurons of the pedunculopontine nucleus in 6-hydroxydopamine-lesioned rats: an in vivo electrophysiological study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

The cholinergic mesopontine tegmentum is a relatively neglected nicotinic master modulator of the dopaminergic system: relevance to drugs of abuse and pathology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Design-based stereology in neuroscience

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Effect of ipsilateral subthalamic nucleus lesioning in a rat parkinsonian model: study of behavior correlated with neuronal activity in the pedunculopontine nucleus.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Noninvasive in vivo assessment of cholinergic cortical circuits in AD using transcranial magnetic stimulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

On the relationships between the striatum and the pedunculopontine tegmental nucleus.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Ionic mechanisms involved in the spontaneous firing of tegmental pedunculopontine nucleus neurons of the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Total number of neurons in the neostriatal, pallidal, subthalamic, and substantia nigral nuclei of the rat basal ganglia: a stereological study using the cavalieri and optical disector methods

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Cholinergic, GABAergic, and glutamate-enriched inputs from the mesopontine tegmentum to the subthalamic nucleus in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Anatomical and electrophysiological studies on the reciprocal projections between the subthalamic nucleus and nucleus tegmenti pedunculopontinus in the rat

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Innervation of substantia nigra neurons by cholinergic afferents from pedunculopontine nucleus in the rat: neuroanatomical and electrophysiological evidence

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4580350

Fusion of diphtheria toxin and urotensin II produces a neurotoxin selective for cholinergic neurons in the rat mesopontine tegmentum.

20 June 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

A non-cholinergic neuronal loss in the pedunculopontine nucleus of toxin-evoked parkinsonian rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Bilateral deep brain stimulation of the pedunculopontine nucleus for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Pedunculopontine nucleus deep brain stimulation produces sustained improvement in primary progressive freezing of gait.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Unilateral pedunculopontine stimulation improves falls in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Pedunculopontine nucleus electric stimulation alleviates akinesia independently of dopaminergic mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

GABAergic neuron distribution in the pedunculopontine nucleus defines functional subterritories.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Cholinergic brainstem neurons modulate cortical gamma activity during slow oscillations

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Electrophysiological properties of pedunculopontine neurons and their postsynaptic responses following stimulation of substantia nigra reticulata

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Electrophysiological effects of orexins/hypocretins on pedunculopontine tegmental neurons in rats: an in vitro study

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

NADPH-diaphorase: a selective histochemical marker for the cholinergic neurons of the pontine reticular formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Cholinergic and noncholinergic tegmental pedunculopontine projection neurons in rats revealed by intracellular labeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Unilateral lesion of the nigrostriatal pathway induces an increase of neuronal activity of the pedunculopontine nucleus, which is reversed by the lesion of the subthalamic nucleus in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Altered sensorimotor integration in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Cholinergic modulation of vibrissal receptive fields in trigeminal nuclei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Parkinson disease: from pathology to molecular disease mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Dopamine regulates the impact of the cerebral cortex on the subthalamic nucleus-globus pallidus network

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Testing forelimb placing "across the midline" reveals distinct, lesion-dependent patterns of recovery in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Gait disorders in parkinsonian monkeys with pedunculopontine nucleus lesions: a tale of two systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Dopaminergic agonists and muscarinic antagonists improve lateralization in hemiparkinsonian rats in a novel exploratory Y-maze

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Unbiased stereological estimation of the number of neurons in the human hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0044-5

Pedunculopontine nucleus stimulation improves akinesia in a Parkinsonian monkey

21 January 2018

1 reference

12 December 2020

Loss of pedunculopontine neurons in progressive supranuclear palsy

1 reference

12 December 2020

Morphological study of the tegmental pedunculopontine nucleus, substantia nigra and subthalamic nucleus, and their interconnections in rat organotypic culture

1 reference

12 December 2020

Pedunculopontine tegmental nucleus of the rat: cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum

1 reference

12 December 2020

10.1186/S13024-015-0044-5

Identifiers

DOI

1 reference

Dimensions Publication ID

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

26394842

1 reference