(Q30670267)

26 June 2017

Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein (English)

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26 June 2017

7

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26 June 2017

Angelo M Facchiano

2

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Pierre Hainaut

object named as

Pierre Hainaut

6

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author name string

Andrew C R Martin

1

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26 June 2017

Alison L Cuff

3

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26 June 2017

Tina Hernandez-Boussard

4

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26 June 2017

Magali Olivier

5

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26 June 2017

1 February 2002

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26 June 2017

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26 June 2017

19

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26 June 2017

2

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26 June 2017

149-164

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Codon 72 polymorphism of the TP53 gene

26 June 2017

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Hydrogen bonding in globular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Refined solution structure of the oligomerization domain of the tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

p53 sweeps through cancer research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

p53: at the crossroads of molecular carcinogenesis and risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Role of the newer p53 family proteins in malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

A mutation data matrix for transmembrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Principles of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Prediction of protein-protein interaction sites using patch analysis

21 January 2018

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https://api.crossref.org/works/10.1002%2FHUMU.10032

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Regulation of p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

X-SITE: use of empirically derived atomic packing preferences to identify favourable interaction regions in the binding sites of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

The interpretation of protein structures: Estimation of static accessibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Recommendations on predictive testing for germ line p53 mutations among cancer-prone individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Twenty years of p53 research: structural and functional aspects of the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Satisfying hydrogen bonding potential in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Raster3D: photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

p53 mutations: gains or losses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Crystallization and structure solution of p53 (residues 326-356) by molecular replacement using an NMR model as template

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Mechanism of rescue of common p53 cancer mutations by second-site suppressor mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Information-theoretical entropy as a measure of sequence variability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Structure of proteins with single-site mutations: a minimum perturbation approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Calculating three-dimensional changes in protein structure due to amino-acid substitutions: the variable region of immunoglobulins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

p53 function and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

21 January 2018

Surfing the p53 network

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https://api.crossref.org/works/10.1002%2FHUMU.10032

Evolutionary conservation and somatic mutation hotspot maps of p53: correlation with p53 protein structural and functional features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Evidence for a distinct inhibitory factor in the regulation of p53 functional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Hot-spot mutants of p53 core domain evince characteristic local structural changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

21 January 2018

X-rays strike p53 again

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10032

21 January 2018

Identifiers

DOI

10.1002/HUMU.10032

1 reference

26 June 2017

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