(Q30725877)

26 June 2017

title

A method for computational combinatorial peptide design of inhibitors of Ras protein (English)

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26 June 2017

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computational biology

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Zeng J

1

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26 June 2017

Treutlein HR

series ordinal

2

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26 June 2017

publication date

1 June 1999

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Protein Engineering Design and Selection

26 June 2017

published in

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26 June 2017

volume

12

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26 June 2017

issue

6

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26 June 2017

page(s)

457-468

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https://api.crossref.org/works/10.1093%2FPROTEIN%2F12.6.457

26 June 2017

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Modern computational chemistry and drug discovery: structure generating programs

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The computer program LUDI: a new method for the de novo design of enzyme inhibitors

21 January 2018

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The structural basis of the activation of Ras by Sos

21 January 2018

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Designing amino acids to determine the local conformations of peptides

21 January 2018

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Computational combinatorial ligand design: application to human alpha-thrombin.

21 January 2018

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Increasing complexity of Ras signaling.

21 January 2018

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Critical binding and regulatory interactions between Ras and Raf occur through a small, stable N-terminal domain of Raf and specific Ras effector residues

21 January 2018

1 reference

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Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function

21 January 2018

1 reference

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Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy

21 January 2018

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Docking flexible ligands to macromolecular receptors by molecular shape

21 January 2018

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Note on Exchange Phenomena in the Thomas Atom

21 January 2018

1 reference

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Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation

21 January 2018

1 reference

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HOOK: a program for finding novel molecular architectures that satisfy the chemical and steric requirements of a macromolecule binding site

21 January 2018

1 reference

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Chemical shift assignments and folding topology of the Ras-binding domain of human Raf-1 as determined by heteronuclear three-dimensional NMR spectroscopy.

21 January 2018

1 reference

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A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

21 January 2018

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Application of the three-dimensional structures of protein target molecules in structure-based drug design

21 January 2018

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Design and synthesis of potent and highly selective thrombin inhibitors

21 January 2018

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VMD: visual molecular dynamics

21 January 2018

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Use of the multiple copy simultaneous search (MCSS) method to design a new class of picornavirus capsid binding drugs.

21 January 2018

1 reference

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Structural characteristics of alpha-helical peptide molecules containing Aib residues

21 January 2018

1 reference

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Alpha-helix and mixed 3(10)/alpha-helix in cocrystallized conformers of Boc-Aib-Val-Aib-Aib-Val-Val-Val-Aib-Val-Aib-OMe

21 January 2018

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A geometric approach to macromolecule-ligand interactions

21 January 2018

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CAVEAT: a program to facilitate the design of organic molecules

21 January 2018

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An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ

21 January 2018

1 reference

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All-atom empirical potential for molecular modeling and dynamics studies of proteins

21 January 2018

1 reference

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Regulation of the Ras signalling network

21 January 2018

1 reference

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The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FPROTEIN%2F12.6.457

Ras/Rap effector specificity determined by charge reversal

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FPROTEIN%2F12.6.457

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

1 reference

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Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FPROTEIN%2F12.6.457

RASMOL: biomolecular graphics for all

21 January 2018

1 reference

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The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

21 January 2018

1 reference

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Effects of salt bridges on protein structure and design.

21 January 2018

1 reference

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

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Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase

21 January 2018

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A study of the active site of influenza virus sialidase: an approach to the rational design of novel anti-influenza drugs

21 January 2018

1 reference

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Protein-protein recognition: an experimental and computational study of the R89K mutation in Raf and its effect on Ras binding

21 January 2018

1 reference

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Structure-based drug design

21 January 2018

1 reference

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Further development of hydrogen bond functions for use in determining energetically favorable binding sites on molecules of known structure. 2. Ligand probe groups with the ability to form more than two hydrogen bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FPROTEIN%2F12.6.457

21 January 2018

Identifiers

DOI

10.1093/PROTEIN/12.6.457

1 reference

26 June 2017

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