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Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations.
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Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
title
Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
main subject
CRISPR
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Cas9
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author
Martin Jínek
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4
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Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
Giulia Palermo
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1
1 reference
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Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
Yinglong Miao
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2
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Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
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26 March 2020
author name string
Ross C Walker
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3
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5084073
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
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26 March 2020
J Andrew McCammon
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5
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Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
publication date
9 September 2016
1 reference
stated in
Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
published in
ACS Central Science
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PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
volume
2
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PMC publication ID
5084073
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retrieved
26 March 2020
issue
10
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Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
page(s)
756-763
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PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
cites work
Detecting Allosteric Networks Using Molecular Dynamics Simulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Protein Allostery and Conformational Dynamics.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Allosteric Pathways in the PPARγ-RXRα nuclear receptor complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Molecular Simulations Highlight the Role of Metals in Catalysis and Inhibition of Type II Topoisomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Conformational control of DNA target cleavage by CRISPR-Cas9.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Engineered CRISPR-Cas9 nucleases with altered PAM specificities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
The structural biology of CRISPR-Cas systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Rational design of a split-Cas9 enzyme complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Catalytic metal ions and enzymatic processing of DNA and RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Genome editing. The new frontier of genome engineering with CRISPR-Cas9
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Programmable RNA recognition and cleavage by CRISPR/Cas9.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Development and applications of CRISPR-Cas9 for genome engineering
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Refinement of the Cornell et al. Nucleic Acids Force Field Based on Reference Quantum Chemical Calculations of Glycosidic Torsion Profiles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Phosphodiester cleavage in ribonuclease H occurs via an associative two-metal-aided catalytic mechanism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Refinement of the AMBER force field for nucleic acids: improving the description of alpha/gamma conformers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Scalable molecular dynamics with NAMD
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
GROMACS: fast, flexible, and free
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
VMD: visual molecular dynamics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
A general two-metal-ion mechanism for catalytic RNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Essential dynamics of proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
21 June 2018
Nucleic Acid-Dependent Conformational Changes in CRISPR-Cas9 Revealed by Site-Directed Spin Labeling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
25 November 2018
Who Activates the Nucleophile in Ribozyme Catalysis? An Answer from the Splicing Mechanism of Group II Introns.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5084073
retrieved
25 November 2018
Generalized correlation for biomolecular dynamics
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27800559
retrieved
12 December 2020
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inferred from PubMed ID database lookup
Identifiers
DOI
10.1021/ACSCENTSCI.6B00218
1 reference
stated in
Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
PMC publication ID
5084073
1 reference
stated in
Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
PubMed publication ID
27800559
1 reference
stated in
Europe PubMed Central
PMC publication ID
5084073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27800559%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 March 2020
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