(Q34509196)

2 August 2017

title

Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering (English)

1 reference

2 August 2017

0 references

3

Jennifer A Doudna

1 reference

2 August 2017

Addison V Wright

1

1 reference

2 August 2017

James K Nuñez

series ordinal

2

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 January 2016

1 reference

2 August 2017

1 reference

2 August 2017

volume

164

1 reference

2 August 2017

issue

1-2

1 reference

2 August 2017

page(s)

29-44

1 reference

Multiplex genome engineering using CRISPR/Cas systems

2 August 2017

cites work

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.1231143

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NBT.2508

CRISPR-Cas systems: beyond adaptive immunity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Mechanism of foreign DNA recognition by a CRISPR RNA-guided surveillance complex from Pseudomonas aeruginosa

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Bacteriophage resistance mechanisms

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cutting it close: CRISPR-associated endoribonuclease structure and function

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

High-resolution transcriptome maps reveal strain-specific regulatory features of multiple Campylobacter jejuni isolates

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

First indication for a functional CRISPR/Cas system in Francisella tularensis

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Guide RNA functional modules direct Cas9 activity and orthogonality

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Directional R-Loop Formation by the CRISPR-Cas Surveillance Complex Cascade Provides Efficient Off-Target Site Rejection.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Identification and characterization of E. coli CRISPR-cas promoters and their silencing by H-NS.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Eukaryotic Argonautes come into focus

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Prokaryotic silencing (psi)RNAs in Pyrococcus furiosus

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR adaptive immune systems of Archaea

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Recognition and maturation of effector RNAs in a CRISPR interference pathway

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

DNase H Activity of Neisseria meningitidis Cas9.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Integrase-mediated spacer acquisition during CRISPR-Cas adaptive immunity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Beyond genome sequencing: lineage tracking with barcodes to study the dynamics of evolution, infection, and cancer.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

End-resection at DNA double-strand breaks in the three domains of life

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Evolutionary conservation of sequence and secondary structures in CRISPR repeats

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Covalent Modification of Bacteriophage T4 DNA Inhibits CRISPR-Cas9.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Regulation of the Type I-F CRISPR-Cas system by CRP-cAMP and GalM controls spacer acquisition and interference

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR immunity drives rapid phage genome evolution in Streptococcus thermophilus

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Identification, structural, and biochemical characterization of a group of large Csn2 proteins involved in CRISPR-mediated bacterial immunity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Small CRISPR RNAs guide antiviral defense in prokaryotes

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Short motif sequences determine the targets of the prokaryotic CRISPR defence system

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structures of the RNA-guided surveillance complex from a bacterial immune system

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Evolution and classification of the CRISPR-Cas systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

DNA motifs determining the efficiency of adaptation into the Escherichia coli CRISPR array

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Pervasive generation of oppositely oriented spacers during CRISPR adaptation

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Small molecule-triggered Cas9 protein with improved genome-editing specificity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

In vitro reconstitution of an Escherichia coli RNA-guided immune system reveals unidirectional, ATP-dependent degradation of DNA target

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Phage response to CRISPR-encoded resistance in Streptococcus thermophilus

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Multiple mechanisms for CRISPR-Cas inhibition by anti-CRISPR proteins

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Solution properties of the archaeal CRISPR DNA repeat-binding homeodomain protein Cbp2.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Crystal Structure of Staphylococcus aureus Cas9

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

A genome-wide view of the expression and processing patterns of Thermus thermophilus HB8 CRISPR RNAs

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Recognition and Cleavage of a Nonstructured CRISPR RNA by Its Processing Endoribonuclease Cas6

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

A Conserved Structural Chassis for Mounting Versatile CRISPR RNA-Guided Immune Responses

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Co-transcriptional DNA and RNA Cleavage during Type III CRISPR-Cas Immunity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Conformational control of DNA target cleavage by CRISPR-Cas9.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

In vivo genome editing using Staphylococcus aureus Cas9

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structure Principles of CRISPR-Cas Surveillance and Effector Complexes

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

I can see CRISPR now, even when phage are gone: a view on alternative CRISPR-Cas functions from the prokaryotic envelope

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Classification and evolution of type II CRISPR-Cas systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Self versus non-self discrimination during CRISPR RNA-directed immunity.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

A new group of phage anti-CRISPR genes inhibits the type I-E CRISPR-Cas system of Pseudomonas aeruginosa

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

An updated evolutionary classification of CRISPR-Cas systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Double-strand DNA end-binding and sliding of the toroidal CRISPR-associated protein Csn2.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

The basic building blocks and evolution of CRISPR-CAS systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

RNA-protein analysis using a conditional CRISPR nuclease

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR adaptation biases explain preference for acquisition of foreign DNA

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

High-throughput analysis of type I-E CRISPR/Cas spacer acquisition in E. coli

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR-Cas: New Tools for Genetic Manipulations from Bacterial Immunity Systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Affinity purification of T7 RNA transcripts with homogeneous ends using ARiBo and CRISPR tags

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

A split-Cas9 architecture for inducible genome editing and transcription modulation

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Unravelling the structural and mechanistic basis of CRISPR-Cas systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Crystal structure of the CRISPR-Cas RNA silencing Cmr complex bound to a target analog

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

In vivo protein interactions and complex formation in the Pectobacterium atrosepticum subtype I-F CRISPR/Cas System

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

The subtype I-F CRISPR-Cas system influences pathogenicity island retention in Pectobacterium atrosepticum via crRNA generation and Csy complex formation

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Detection and characterization of spacer integration intermediates in type I-E CRISPR-Cas system

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Annotation and Classification of CRISPR-Cas Systems.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Crystal Structure of Streptococcus pyogenes Csn2 Reveals Calcium-Dependent Conformational Changes in Its Tertiary and Quaternary Structure

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

A novel interference mechanism by a type IIIB CRISPR-Cmr module in Sulfolobus.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Foreign DNA capture during CRISPR-Cas adaptive immunity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR-based adaptive and heritable immunity in prokaryotes

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Mechanism of substrate selection by a highly specific CRISPR endoribonuclease

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cas9 function and host genome sampling in Type II-A CRISPR-Cas adaptation

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: Evidence for a one-step transesterification mechanism

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Adaptation in bacterial CRISPR-Cas immunity can be driven by defective phages.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Strong bias in the bacterial CRISPR elements that confer immunity to phage.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structural basis for CRISPR RNA-guided DNA recognition by Cascade

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Characterization of the CRISPR/Cas subtype I-A system of the hyperthermophilic crenarchaeon Thermoproteus tenax

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Genome engineering using Adeno-Associated Virus (AAV).

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cas9 specifies functional viral targets during CRISPR-Cas adaptation.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Expanding the Biologist's Toolkit with CRISPR-Cas9

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Photoactivatable CRISPR-Cas9 for optogenetic genome editing

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR-spacer integration reporter plasmids reveal distinct genuine acquisition specificities among CRISPR-Cas I-E variants of Escherichia coli

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

To acquire or resist: the complex biological effects of CRISPR-Cas systems

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Efficient programmable gene silencing by Cascade

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3)

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Rational design of a split-Cas9 enzyme complex

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Programmable RNA shredding by the type III-A CRISPR-Cas system of Streptococcus thermophilus.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

RecBCD enzyme and the repair of double-stranded DNA breaks

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Delivery and Specificity of CRISPR-Cas9 Genome Editing Technologies for Human Gene Therapy.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Sequences spanning the leader-repeat junction mediate CRISPR adaptation to phage in Streptococcus thermophilus

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Toroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from Sulfolobus solfataricus

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

SCIENCE POLICY. U.S. to review agricultural biotech regulations.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

CRISPR interference directs strand specific spacer acquisition

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Efficient intracellular delivery of native proteins

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Identification of genes that are associated with DNA repeats in prokaryotes

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2015.12.035

Identifiers

DOI

10.1016/J.CELL.2015.12.035

1 reference

2 August 2017

1 reference