(Q30848784)

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Probing the specificity of cysteine proteinases at subsites remote from the active site: analysis of P4, P3, P2' and P3' variations in extended substrates.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Probing the specificity of cysteine proteinases at subsites remote from the active site: analysis of P4, P3, P2' and P3' variations in extended substrates (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Euridice Carmona

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

F C Portaro

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

A B Santos

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

M H Cezari

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

M A Juliano

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

L Juliano

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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publication date

1 April 2000

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

347 Pt 1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

123-129

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Statistical estimations in enzyme kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Fluorescence-quenched solid phase combinatorial libraries in the characterization of cysteine protease substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Revised definition of substrate binding sites of papain-like cysteine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Major increase in endopeptidase activity of human cathepsin B upon removal of occluding loop contacts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

The crystal structure of human cathepsin L complexed with E-64

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Endosomal proteolysis of internalized proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

X-ray crystallographic structure of a papain-leupeptin complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Characterization of cathepsin B specificity by site-directed mutagenesis. Importance of Glu245 in the S2-P2 specificity for arginine and its role in transition state stabilization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Crystal structure of glycyl endopeptidase from Carica papaya: a cysteine endopeptidase of unusual substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Structure of papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Mapping the active site of papain with the aid of peptide substrates and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Crystal structure of a papain-E-64 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Cysteinyl proteinases and their selective inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

A protein engineering study of the role of aspartate 158 in the catalytic mechanism of papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Intramolecularly quenched fluorogenic tetrapeptide substrates for tissue and plasma kallikreins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Rat procathepsin B. Proteolytic processing to the mature form in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Inhibiting tissue invasion and metastasis as targets for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Comparative behaviour of calpain and cathepsin B toward peptidyl acyloxymethyl ketones, sulphonium methyl ketones and other potential inhibitors of cysteine proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Crystal structure of papain-E64-c complex. Binding diversity of E64-c to papain S2 and S3 subsites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

Binding of chloromethyl ketone substrate analogues to crystalline papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220939

21 June 2018

New intramolecularly quenched fluorogenic peptide substrates for the study of the kinetic specificity of papain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of P2' substituents on kinetic constants for hydrolysis by cysteine proteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Action of cathepsin L on the oxidized B-chain of bovine insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid analysis by reverse-phase high-performance liquid chromatography: precolumn derivatization with phenylisothiocyanate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Participation of cathepsin L on bone resorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The specificity of the S1' subsite of cysteine proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new, sensitive fluorogenic substrate for papain based on the sequence of the cystatin inhibitory site

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic mechanism in papain family of cysteine peptidases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alignment/phylogeny of the papain superfamily of cysteine proteases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the S3 Subsite Specificity of Cathepsin B

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the occluding loop in cathepsin B activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding mode of CA074, a specific irreversible inhibitor, to bovine cathepsin B as determined by X-ray crystal analysis of the complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Revisiting the S2 specificity of papain by structural analogs of Phe

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interdependency of sequence and positional specificities for cysteine proteases of the papain family

1 reference

https://pubmed.ncbi.nlm.nih.gov/10727410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3470123

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

10.1042/BJ3470123

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10727410%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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