(Q30850215)

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Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease

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Europe PubMed Central

PMC publication ID

14 September 2017

Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Ronald Swanstrom

4

object named as

Ronald Swanstrom

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Steven C. Pettit

1 reference

ORCID Public Data File 2021

Celia A. Schiffer

3

object named as

Celia A Schiffer

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

Steve C Pettit

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Gavin J Henderson

2

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Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

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publication date

1 October 2002

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Virology

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Europe PubMed Central

PMC publication ID

14 September 2017

76

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

20

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

10226-10233

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136535

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HIV-1 protease: maturation, enzyme specificity, and drug resistance.

1 reference

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How does a symmetric dimer recognize an asymmetric substrate? A substrate complex of HIV-1 protease

1 reference

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Resistance-associated loss of viral fitness in human immunodeficiency virus type 1: phenotypic analysis of protease and gag coevolution in protease inhibitor-treated patients

1 reference

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21 June 2018

Sequential steps in human immunodeficiency virus particle maturation revealed by alterations of individual Gag polyprotein cleavage sites.

1 reference

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21 June 2018

Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly

1 reference

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Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites

1 reference

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Determinants of the human immunodeficiency virus type 1 p15NC-RNA interaction that affect enhanced cleavage by the viral protease.

1 reference

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Analysis of cleavage site mutations between the NC and PR Gag domains of Rous sarcoma virus

1 reference

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Ultrastructure and morphogenesis of human immunodeficiency virus

1 reference

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Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors

1 reference

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21 June 2018

Human immunodeficiency virus, type 1 protease substrate specificity is limited by interactions between substrate amino acids bound in adjacent enzyme subsites

1 reference

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21 June 2018

Comparison of the substrate-binding pockets of the Rous sarcoma virus and human immunodeficiency virus type 1 proteases.

1 reference

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21 June 2018

Structure-based inhibitors of HIV-1 protease

1 reference

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21 June 2018

The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency.

1 reference

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21 June 2018

Cleavage of p15 protein in vitro by human immunodeficiency virus type 1 protease is RNA dependent

1 reference

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21 June 2018

The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions.

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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A new pathway in the generation of defective retrovirus DNA

1 reference

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High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

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21 June 2018

Immunological and chemical analysis of P6, the carboxyl-terminal fragment of HIV P15.

1 reference

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21 June 2018

Molecular characterization of gag proteins from simian immunodeficiency virus (SIVMne).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136535

21 June 2018

The gag gene products of human immunodeficiency virus type 1: alignment within the gag open reading frame, identification of posttranslational modifications, and evidence for alternative gag precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136535

21 June 2018

HIV expression strategies: ribosomal frameshifting is directed by a short sequence in both mammalian and yeast systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136535

21 June 2018

Synthetic peptides as substrates and inhibitors of human immune deficiency virus-1 protease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136535

21 June 2018

Complete nucleotide sequences of functional clones of the AIDS virus

1 reference

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21 June 2018

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1 reference

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21 June 2018

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136535

21 June 2018

The use of native T7 DNA polymerase for site-directed mutagenesis

1 reference

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21 June 2018

Peptide substrates and inhibitors of the HIV-1 protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136535

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Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides

1 reference

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Mutations of the precursor to the terminal protein of adenovirus serotypes 2 and 5.

1 reference

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Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1 reference

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Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

1 reference

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Gag precursors of HIV and SIV are cleaved into six proteins found in the mature virions

1 reference

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21 June 2018

Retroviral proteinases

1 reference

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21 June 2018

Specificity and inhibition of proteases from human immunodeficiency viruses 1 and 2

1 reference

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Mutational analysis of a native substrate of the human immunodeficiency virus type 1 proteinase

1 reference

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21 June 2018

Sensitive, soluble chromogenic substrates for HIV-1 proteinase

1 reference

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Mutating P2 and P1 residues at cleavage junctions in the HIV-1 pol polyprotein. Effects on hydrolysis by HIV-1 proteinase.

1 reference

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21 June 2018

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1 reference

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1 reference

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Mutagenesis of protease cleavage sites in the human immunodeficiency virus type 1 gag polyprotein

1 reference

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Efficient site-directed mutagenesis using uracil-containing DNA.

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136535

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Analysis of retroviral protease cleavage sites reveals two types of cleavage sites and the structural requirements of the P1 amino acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136535

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Specific inhibitor of human immunodeficiency virus proteinase prevents the cytotoxic effects of a single-chain proteinase dimer and restores particle formation

1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/12239298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-resistant HIV-1 proteases identify enzyme residues important for substrate selection and catalytic rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/12239298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of HIV-1 gag polyprotein synthesized in vitro: sequential cleavage by the viral protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12239298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrolysis of synthetic chromogenic substrates by HIV-1 and HIV-2 proteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12239298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12239298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 protease specificity derived from a complex mixture of synthetic substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/12239298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the amino-terminal core domain of the HIV-1 capsid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12239298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.76.20.10226-10233.2002

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

release_djetbl4cgnh67pxxzfery624ri

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https://api.fatcat.wiki/v0/release/djetbl4cgnh67pxxzfery624ri

24 November 2022

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mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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