(Q30870479)

27 June 2017

PKN binds and phosphorylates human papillomavirus E6 oncoprotein (English)

1 reference

27 June 2017

0 references

Gao Q

1

1 reference

27 June 2017

Kumar A

2

1 reference

27 June 2017

Srinivasan S

3

1 reference

27 June 2017

Singh L

4

1 reference

27 June 2017

Mukai H

5

1 reference

27 June 2017

Ono Y

6

1 reference

27 June 2017

Wazer DE

7

1 reference

27 June 2017

Band V

8

1 reference

27 June 2017

language of work or name

English

0 references

publication date

1 May 2000

1 reference

Journal of Biological Chemistry

27 June 2017

1 reference

27 June 2017

275

1 reference

27 June 2017

20

1 reference

27 June 2017

14824-14830

1 reference

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

27 June 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

p53; from inductive signal to cellular effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Telomerase activation by the E6 gene product of human papillomavirus type 16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Telomerase activity, cell proliferation, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Telomeres and senescence: the history, the experiment, the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Refining the telomere-telomerase hypothesis of aging and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

21 January 2018

Myc activates telomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Direct activation of TERT transcription by c-MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Interaction of papillomavirus E6 oncoproteins with a putative calcium-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Inhibition of Bak-induced apoptosis by HPV-18 E6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

E3-ubiquitin ligase/E6-AP links multicopy maintenance protein 7 to the ubiquitination pathway by a novel motif, the L2G box

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

A novel protein kinase with leucine zipper-like sequences: its catalytic domain is highly homologous to that of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Activation of PKN, a novel 120-kDa protein kinase with leucine zipper-like sequences, by unsaturated fatty acids and by limited proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Proteolytic activation of PKN by caspase-3 or related protease during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Human papillomavirus (HPV) type 18 E7 protein is a short-lived steroid-inducible phosphoprotein in HPV-transformed cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Negative charge at the casein kinase II phosphorylation site is important for transformation but not for Rb protein binding by the E7 protein of human papillomavirus type 16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Mutations of the human papillomavirus type 16 E7 gene that affect transformation, transactivation and phosphorylation by the E7 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Expression, purification and characterization of the ubiquitous protein kinase C-related kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Multiple interactions of PRK1 with RhoA. Functional assignment of the Hr1 repeat motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Mutational analysis of the regulatory mechanism of PKN: the regulatory region of PKN contains an arachidonic acid-sensitive autoinhibitory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Activation of PRK1 by phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. A comparison with protein kinase C isotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Paxillin: a cytoskeletal target for tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

The replication functions of SV40 T antigen are regulated by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Tyrosine phosphorylation is a signal for the trafficking of pp85, an 85-kDa phosphorylated polypeptide associated with phosphatidylinositol kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Association of Polyomavirus middle tumor antigen with phospholipase C-gamma 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Phosphatidylinositol metabolism and polyoma-mediated transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Phosphorylation of middle T by pp60c-src: a switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Biochemical and crystallographic characterization of a Rho effector domain of the protein serine/threonine kinase N in a complex with RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

Characterization of the interaction between RhoA and the amino-terminal region of PKN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.20.14824

21 January 2018

Identifiers

DOI

10.1074/JBC.275.20.14824

1 reference

27 June 2017

1 reference