(Q30878526)

27 June 2017

title

Advances in the use of synthetic combinatorial chemistry: mixture-based libraries (English)

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27 June 2017

Clemencia Pinilla

1

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27 June 2017

Jon R Appel

series ordinal

2

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27 June 2017

Eva Borràs

series ordinal

3

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27 June 2017

Richard A Houghten

series ordinal

4

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27 June 2017

language of work or name

English

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publication date

1 January 2003

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27 June 2017

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27 June 2017

volume

9

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27 June 2017

issue

1

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27 June 2017

page(s)

118-122

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Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

27 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

A new general approach for the simultaneous chemical synthesis of large numbers of oligonucleotides: segmental solid supports

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Synthesis and Applications of Small Molecule Libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

The Current Status of Heterocyclic Combinatorial Libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Comprehensive survey of combinatorial library synthesis: 2000.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

"Libraries from libraries": chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Combinatorial chemistry toward understanding the function(s) of carbohydrates and carbohydrate conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

A new type of synthetic peptide library for identifying ligand-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

The identification of CD4+ T cell epitopes with dedicated synthetic peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Mixture-based synthetic combinatorial libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

A priori delineation of a peptide which mimics a discontinuous antigenic determinant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

The "One-Bead-One-Compound" Combinatorial Library Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Complex synthetic chemical libraries indexed with molecular tags

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

A combinatorial library of indinavir analogues and its in vitro and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Definition of the extended substrate specificity determinants for beta-tryptases I and II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Cercarial elastase is encoded by a functionally conserved gene family across multiple species of schistosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Substrate specificity of schistosome versus human legumain determined by P1-P3 peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Altered substrate specificity of drug-resistant human immunodeficiency virus type 1 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Global analysis of proteasomal substrate specificity using positional-scanning libraries of covalent inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Substrate specificity of the human proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Tethered libraries: solid-phase synthesis of substituted urea-linked bicyclic guanidines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Investigation of antigen-antibody interactions using a soluble, non-support-bound synthetic decapeptide library composed of four trillion (4 x 10(12) sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Exploring immunological specificity using synthetic peptide combinatorial libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Combinatorial peptide libraries and biometric score matrices permit the quantitative analysis of specific and degenerate interactions between clonotypic TCR and MHC peptide ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Enhanced immune activity of cytotoxic T-lymphocyte epitope analogs derived from positional scanning synthetic combinatorial libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Contribution of individual amino acids within MHC molecule or antigenic peptide to TCR ligand potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Combinatorial peptide library-based identification of peptide ligands for tumor-reactive cytolytic T lymphocytes of unknown specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Mimotopes for tumor-specific T lymphocytes in human cancer determined with combinatorial peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Findings on T cell specificity revealed by synthetic combinatorial libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Inhibition of beta-amyloid-induced neurotoxicity by imidazopyridoindoles derived from a synthetic combinatorial library

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Combinatorial synthesis of 3-(amidoalkyl) and 3-(aminoalkyl)-2-arylindole derivatives: discovery of potent ligands for a variety of G-protein coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Identification of novel antitumor agents from mixture-based synthetic combinatorial libraries using cell-based assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Synthesis of 7200 small molecules based on a substructural analysis of the histone deacetylase inhibitors trichostatin and trapoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

21 January 2018

Solid phase synthesis

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

Simultaneous pharmacokinetic screening of a mixture of compounds in the dog using API LC/MS/MS analysis for increased throughput

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0103-118

21 January 2018

Identifiers

DOI

10.1038/NM0103-118

1 reference

Dimensions Publication ID

27 June 2017

1024852559

0 references

1 reference