(Q30878932)

English

Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay

scientific article published on June 2000

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay (English)

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

1 reference

based on heuristic

inferred from title

author name string

Parnot C

1

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

Bardin S

2

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

Miserey-Lenkei S

3

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

Guedin D

4

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

Corvol P

5

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

Clauser E

6

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

language of work or name

0 references

publication date

1 June 2000

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

97

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

13

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

7615-7620

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

Pathology of the TSH receptor

1 reference

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21 June 2018

Use of constitutive G protein-coupled receptor activity for drug discovery.

1 reference

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C5a receptor activation. Genetic identification of critical residues in four transmembrane helices

1 reference

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21 June 2018

Mechanism of constitutive activation of the AT1 receptor: influence of the size of the agonist switch binding residue Asn(111).

1 reference

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21 June 2018

Activating Smoothened mutations in sporadic basal-cell carcinoma

1 reference

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21 June 2018

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

1 reference

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Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide

1 reference

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A live-cell assay for studying extracellular and intracellular endothelin-converting enzyme activity.

1 reference

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21 June 2018

The conformational change responsible for AT1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

The cubic ternary complex receptor-occupancy model. III. resurrecting efficacy

1 reference

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21 June 2018

The classification of seven transmembrane receptors in recombinant expression systems

1 reference

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21 June 2018

Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Constitutive activation of a single effector pathway: evidence for multiple activation states of a G protein-coupled receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide

1 reference

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21 June 2018

Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Specialized ribosomes allow for the study of mutations in functionally important regions in 16 S rRNA, without affecting cell growth. The identification of functional regions in the central domain of 16S rRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Synthetic cDNA encoding the rat AT1a receptor: a useful tool for structure-function relationship analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model

1 reference

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21 June 2018

Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Constitutive activation of muscarinic receptors by the G-protein Gq.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Randomization of genes by PCR mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16594

21 June 2018

Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin

1 reference

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

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21 June 2018

Mutation of Asn111 in the third transmembrane domain of the AT1A angiotensin II receptor induces its constitutive activation.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110142297

21 January 2018

Improved green fluorescent protein by molecular evolution using DNA shuffling

1 reference

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Heterozygous missense mutation in the rhodopsin gene as a cause of congenital stationary night blindness

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic mutations of the angiotensin II (AT1) receptor gene are not present in aldosterone-producing adenoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10852946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutively active G protein-coupled receptors: potential mechanisms of receptor activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10852946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C-terminal third intracellular loop of the rat AT1A angiotensin receptor plays a key role in G protein coupling specificity and transduction of the mitogenic signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/10852946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10852946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.110142297

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

2000PNAS...97.7615P

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

ResearchGate publication ID

0 references

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