(Q30883456)

27 June 2017

1 reference

title

Forward chemical genetics: progress and obstacles on the path to a new pharmacopoeia (English)

1 reference

27 June 2017

R Scott Lokey

1

1 reference

27 June 2017

publication date

1 February 2003

1 reference

Current Opinion in Chemical Biology

27 June 2017

published in

1 reference

27 June 2017

volume

7

1 reference

27 June 2017

issue

1

1 reference

27 June 2017

page(s)

91-96

1 reference

Towards a pharmacological genetics

27 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Chemical genetics resulting from a passion for synthetic organic chemistry.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Isolation of a protein subunit from microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Brefeldin A: the advantage of being uncompetitive

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

High-throughput method for the production and analysis of large natural product libraries for drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Isolating "uncultivable" microorganisms in pure culture in a simulated natural environment

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Isolation of antibiotics turbomycin a and B from a metagenomic library of soil microbial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Target-oriented and diversity-oriented organic synthesis in drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Pairwise use of complexity-generating reactions in diversity-oriented organic synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Toward high-throughput synthesis of complex natural product-like compounds in the genomics and proteomics age.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Solid-phase combinatorial synthesis using MicroKan reactors, Rf tagging, and directed sorting

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

A one-bead, one-stock solution approach to chemical genetics: part 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

A chemical inhibitor of N-WASP reveals a new mechanism for targeting protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Use of isogenic human cancer cells for high-throughput screening and drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Small molecule developmental screens reveal the logic and timing of vertebrate development

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Characterization and quantitation of NF-kappaB nuclear translocation induced by interleukin-1 and tumor necrosis factor-alpha. Development and use of a high capacity fluorescence cytometric system.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Using small molecules to study big questions in cellular microbiology.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Cellular screening assays using fluorescence microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Display cloning: functional identification of natural product receptors using cDNA-phage display

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Identification of hNopp140 as a binding partner for doxorubicin with a phage display cloning method

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

A unique paclitaxel-mediated modulation of the catalytic activity of topoisomerase IIalpha

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Cyclosporine A is an uncompetitive inhibitor of proteasome activity and prevents NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

A GAL4-based yeast three-hybrid system for the identification of small molecule-target protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

The emerging power of chemical genetics

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2802%2900002-9

7 January 2021

10.1016/S1367-5931(02)00002-9

Identifiers

DOI

1 reference

27 June 2017

1 reference