(Q30976982)

27 June 2017

Engineering of a macromolecular scaffold to develop specific protease inhibitors (English)

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27 June 2017

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A Allart Stoop

1

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27 June 2017

Charles S Craik

series ordinal

2

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27 June 2017

language of work or name

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17 August 2003

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27 June 2017

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27 June 2017

21

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27 June 2017

9

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27 June 2017

1063-1068

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MEROPS: the protease database

27 June 2017

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7 January 2021

Quantitation of membrane type serine protease 1 (MT-SP1) in transformed and normal cells

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7 January 2021

Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes

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7 January 2021

Human tissue kallikreins: a new enzymatic cascade pathway?

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7 January 2021

Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue

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7 January 2021

Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity

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7 January 2021

Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains

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7 January 2021

Delineation of prognostic biomarkers in prostate cancer

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7 January 2021

Measurement of Prostate-Specific Antigen in Serum as a Screening Test for Prostate Cancer

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7 January 2021

Immunofluorometric quantitation and histochemical localisation of kallikrein 6 protein in ovarian cancer tissue: a new independent unfavourable prognostic biomarker

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7 January 2021

Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis

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7 January 2021

Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.

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7 January 2021

Small, noncovalent serine protease inhibitors

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7 January 2021

Protease inhibitors: current status and future prospects

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7 January 2021

Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI

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7 January 2021

Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases

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7 January 2021

Macromolecular chelation as an improved mechanism of protease inhibition: structure of the ecotin-trypsin complex.

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7 January 2021

Crystal structure of thrombin-ecotin reveals conformational changes and extended interactions

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7 January 2021

The role of ecotin dimerization in protease inhibition

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7 January 2021

Ecotin is a potent anticoagulant and reversible tight-binding inhibitor of factor Xa.

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7 January 2021

Ecotin is a potent inhibitor of the contact system proteases factor XIIa and plasma kallikrein

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7 January 2021

A plasma kallikrein-dependent plasminogen cascade required for adipocyte differentiation

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7 January 2021

Inhibition of plasma kallikrein prevents peptidoglycan-induced arthritis in the Lewis rat

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7 January 2021

Specific inhibition of plasma kallikrein modulates chronic granulomatous intestinal and systemic inflammation in genetically susceptible rats

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7 January 2021

Potent and selective Kunitz domain inhibitors of plasma kallikrein designed by phage display

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7 January 2021

Iterative optimization of high-affinity protease inhibitors using phage display. 2. Plasma kallikrein and thrombin

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7 January 2021

Rapid evolution of a protein in vitro by DNA shuffling

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7 January 2021

Synthetic shuffling expands functional protein diversity by allowing amino acids to recombine independently

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7 January 2021

Anatomy of hot spots in protein interfaces

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7 January 2021

Engineering bidentate macromolecular inhibitors for trypsin and urokinase-type plasminogen activator

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7 January 2021

Computer-assisted mutagenesis of ecotin to engineer its secondary binding site for urokinase inhibition

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7 January 2021

Selection of chymotrypsin inhibitors from a conformationally-constrained combinatorial peptide library

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7 January 2021

Ecotin: a serine protease inhibitor with two distinct and interacting binding sites

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7 January 2021

Error analysis of chemically synthesized polynucleotides

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7 January 2021

Human plasma prekallikrein, a zymogen to a serine protease that contains four tandem repeats

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7 January 2021

Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa.

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7 January 2021

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site

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7 January 2021

High-density mutagenesis by combined DNA shuffling and phage display to assign essential amino acid residues in protein-protein interactions: application to study structure-function of plasminogen activation inhibitor 1 (PAI-I).

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7 January 2021

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

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7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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7 January 2021

Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein

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7 January 2021

Identifiers

DOI

10.1038/NBT860

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Dimensions Publication ID

27 June 2017

1050497844

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Fatcat ID

release_hdtoqa2oejburc3d2ryky5vyui

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Fatcat

https://api.fatcat.wiki/v0/release/hdtoqa2oejburc3d2ryky5vyui

24 November 2022

mapped directly with Wikidata item

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