(Q30982911)

English

Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia

scientific article published on April 1, 1992

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia (English)

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

1 reference

based on heuristic

inferred from title

alternative mRNA splicing, via spliceosome

1 reference

based on heuristic

inferred from title

human chromosome 17

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

chromosomal translocation

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

neoplasm protein

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

proto-oncogene protein

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

nuclear protein

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

2

object named as

M. Alcalay

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

author name string

P. P. Pandolfi

1

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

M. Fagioli

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

D. Zangrilli

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

A. Mencarelli

5

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12 September 2022

D. Diverio

6

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12 September 2022

A. Biondi

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

F. Lo Coco

8

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12 September 2022

A. Rambaldi

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

F. Grignani

10

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

language of work or name

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publication date

1 April 1992

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

full work available at URL

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1314166/?tool=EBI

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1314166/pdf/?tool=EBI

Portable Document Format

online access status

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

https://europepmc.org/articles/PMC556589

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

https://europepmc.org/articles/PMC556589?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314166

12 September 2022

The EMBO Journal

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

11

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

4

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

1397-1407

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Alternative splicing: a ubiquitous mechanism for the generation of multiple protein isoforms from single genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

The steroid and thyroid hormone receptor superfamily

1 reference

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28 July 2018

fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Zinc fingers: gilt by association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Nuclear receptors enhance our understanding of transcription regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Identification of a receptor for the morphogen retinoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

A human retinoic acid receptor which belongs to the family of nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Gene regulation by steroid hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-alpha)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Zinc fingers and other metal-binding domains. Elements for interactions between macromolecules

1 reference

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A novel cysteine-rich sequence motif

1 reference

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Leukemia and the disruption of normal hematopoiesis

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28 July 2018

Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

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Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid

1 reference

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A reappraisal of non-consensus mRNA splice sites

1 reference

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28 July 2018

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556589

28 July 2018

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1 reference

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Proposals for the Classification of the Acute Leukaemias French-American-British (FAB) Co-operative Group

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28 July 2018

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

1 reference

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Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/1314166

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based on heuristic

inferred from PubMed ID database lookup

RAR-alpha gene rearrangements as a genetic marker for diagnosis and monitoring in acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/1314166

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular evaluation of response to all-trans-retinoic acid therapy in patients with acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/1314166

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

1 reference

https://pubmed.ncbi.nlm.nih.gov/1314166

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1992.TB05185.X

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1314166

12 September 2022

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

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